Results 71 to 80 of about 3,575,020 (315)
Sterol metabolism studies using a combination of isotopic and chromatographic procedures were carried out in rats fed either a low-cholesterol stock diet or a stock diet containing 0.1% cholesterol.
B I Cohen, R F Raicht, E H Mosbach
doaj +1 more source
RESCUING PUBLICNESS FROM ORGANIZATION STUDIES [PDF]
Does publicness still make sense as an issue for further research? Classic organizational sociology (or standard theory) has provided a breakthrough for understanding public administration and management, but has not fully explored the agenda. Publicness
Jean-Claude Thoenig
core
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Redefinition of the Public Management Model in the era of 21st century crises
Objectives The aim of this article is to analyze the relationship between the right to good administration—as a constitutionally and European-level guaranteed individual right—and the paradigm of New Public Management, which promotes efficiency ...
Barbara Anna Kusto, Ewa Bonusiak
doaj +1 more source
Mapping the Swiss Public Administration: Challenges and First Research Steps [PDF]
In the present paper, we argue that the existing data collections fail to map specific features of modern public administration in Switzerland, namely new modes of governance with hybrid state structures. After presenting the Swiss federal administration
Fritz Sager, Frédéric Varone
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The Freedom of Information Act (FOIA): Background, Legislation, and Policy Issues [PDF]
[Excerpt] The Freedom of Information Act (FOIA; 5 U.S.C. §552) allows any person—individual or corporate, citizen or not—to request and obtain, without explanation or justification, existing, identifiable, and unpublished agency records on any topic ...
Ginsberg, Wendy
core +2 more sources
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source

