Results 51 to 60 of about 3,575,020 (315)

The 2014 American State Litter Scorecard FINAL: USA's Dirtiest & Cleanest States Includes Statistics and Charts [PDF]

open access: yes, 2006
A NEW State Litter "Scorecard" is released for the 2014 American Society for Public Administration (ASPA) Conference. Every three years, the Scorecard approximates each state's overall public spaces environmental quality through tried-and-true, hard-to ...
Antoine, J., Vandergheynst, P.
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Health Care Reforms, Power Concentration, and Receding Citizen Participation

open access: yesRisk Management and Healthcare Policy, 2023
Daniel Simonet Department of Management, Strategy & Entrepreneurship, American University of Sharjah, Sharjah, United Arab EmiratesCorrespondence: Daniel Simonet, Email dsimonet@aus.eduAbstract: The article highlights several outstanding features of ...
Simonet D
doaj  

Ineficiência, fragilização e duplicidade. o velho estado novo perante a emigração para frança (1960-1968)

open access: yesLer História, 2009
Between 1960 and 1968, the Portuguese government managed modernization, economic growth and trade openness to Europe in an ambiguous way. This processes that profoundly transformed the society have not been politically accepted.
Victor Pereira
doaj   +1 more source

The New Public Management, a Factor of Novelty in the Public Administration [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2021
In the last decades, the traditional administration has been subjected to some challenges caused by ample changes, worldwide, in the managerial, political, judicial field, against the globalization and diversification of services.
Florina Popa
doaj  

"They see me as mentally ill": the stigmatization experiences of Chinese menopausal women in the family

open access: yesBMC Women's Health, 2023
Background Menopausal women are regarded as “abnormal people” in China and are often discriminated against and ostracized, especially in the privacy of their homes. However, research on the stigmatization of menopausal women in China is limited.
Qiong Li   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Training and Retaining Public Servants for the Future

open access: yesTransylvanian Review of Administrative Sciences
Demographic changes with an ageing popula­tion and declining birth rates, alongside economic challenges, have implications for the public service labour market.
Karen Johnston, Andrew Massey
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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