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Lean Regulation in Public Administration: Preconditions for Implementation and Main Content

Управленческие науки
This article examines the application of lean thinking approaches in public administration. The relevance of this issue is driven by the state’s need to reduce the costs of both regulation itself and decision-making, a goal that is conceptualized in the ...
I. I. Rakhmeeva, M. Yu. Andronov
doaj   +1 more source

Analysis of the Egyptian Model of Public Administration Reform Policies [PDF]

Wadī Al-Nīl Lil Dirāsāt wa Al-Buẖūṯ Al-Insāniyyaẗ wa Al-Iğtimāʿiyyaẗ wa Al-Tarbawiyyaẗ
Starting in the 1950s and continuing up to the present, this study aims to analyze the characteristics and dynamics of Egypt's public administration reform, taking this understanding as a trajectory paradigm for ongoing endeavors in public administration
Ola Abdelmoneim Emara, Karim Nabil Salem
doaj   +1 more source

The New Public Management, a Factor of Novelty in the Public Administration [PDF]

Ovidius University Annals: Economic Sciences Series, 2021
In the last decades, the traditional administration has been subjected to some challenges caused by ample changes, worldwide, in the managerial, political, judicial field, against the globalization and diversification of services.
Florina Popa
doaj  

"They see me as mentally ill": the stigmatization experiences of Chinese menopausal women in the family

BMC Women's Health, 2023
Background Menopausal women are regarded as “abnormal people” in China and are often discriminated against and ostracized, especially in the privacy of their homes. However, research on the stigmatization of menopausal women in China is limited.
Qiong Li, Jintu Gu, Jianyuan Huang, Pei Zhao, Chenliang Luo   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Gestão Pública: entre a visão clássica da Administração Pública e o novo paradigma da Governação Pública

Revista Enfoques, 2009
This text aims at accounting for the evolution of the reform movement that goes from Public Administration to Governance, while going through New Public Management.A movement that to be understood requires, more than a sequence of steps, the ...
André Azevedo Alves, José Manuel Moreira   +1 more
doaj  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Performance Management Systems Productivity in the Public Sector: Wither African Public Administration

Africa’s Public Service Delivery & Performance Review, 2014
Performance management has attracted a lot of debate in the recent past. It is a systematic effort to improve performance through an ongoing process of establishing desired outcomes, setting performance standards to improve performance and productivity ...
Jacob Olufemi Fatile
doaj   +1 more source