Results 41 to 50 of about 3,559,907 (314)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A NEW DECREE ON OFFICE OPERATIONS OF PUBLIC ADMINISTRATION

open access: yesElektronički Zbornik Radova Veleučilišta u Šibeniku, 2022
On 1 July 2021, the Government of the Republic of Croatia accepted a new Decree on Office Operations, which is a key regulation for the operations of public administration throughout the country.
Vesna Jurin Bakotić, Ana Čvrljak
doaj   +1 more source

Health Care Opinion Leaders' Views on Priorities for the Obama Administration [PDF]

open access: yes, 2009
Presents results of a survey of experts on priorities in healthcare reform and related economic stimulus for the Barack Obama administration, including new regulations, employer financing of coverage, and an insurance exchange with a public ...
Karen Davis   +3 more
core  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Local Management and New Public Management

open access: yesCentral European Public Administration Review, 2011
Economic globalization, growingly differentiated and unstable markets, fiscal crises in light of increasing public expenditure are the elements of an uncertain future for local communities.
Irena Bačlija
doaj   +1 more source

The New Public Management, a Factor of Novelty in the Public Administration [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2021
In the last decades, the traditional administration has been subjected to some challenges caused by ample changes, worldwide, in the managerial, political, judicial field, against the globalization and diversification of services.
Florina Popa
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Health Care Reforms, Power Concentration, and Receding Citizen Participation

open access: yesRisk Management and Healthcare Policy, 2023
Daniel Simonet Department of Management, Strategy & Entrepreneurship, American University of Sharjah, Sharjah, United Arab EmiratesCorrespondence: Daniel Simonet, Email dsimonet@aus.eduAbstract: The article highlights several outstanding features of ...
Simonet D
doaj  

Ineficiência, fragilização e duplicidade. o velho estado novo perante a emigração para frança (1960-1968)

open access: yesLer História, 2009
Between 1960 and 1968, the Portuguese government managed modernization, economic growth and trade openness to Europe in an ambiguous way. This processes that profoundly transformed the society have not been politically accepted.
Victor Pereira
doaj   +1 more source

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