Results 51 to 60 of about 3,559,907 (314)

"They see me as mentally ill": the stigmatization experiences of Chinese menopausal women in the family

open access: yesBMC Women's Health, 2023
Background Menopausal women are regarded as “abnormal people” in China and are often discriminated against and ostracized, especially in the privacy of their homes. However, research on the stigmatization of menopausal women in China is limited.
Qiong Li   +4 more
doaj   +1 more source

STRATEGY AS DISCURSIVE PRACTICE IN A BRAZILIAN PUBLIC UNIVERSITY: A LOOK UNDER THE PERSPECTIVE OF CRITICAL DISCOURSE ANALYSIS [PDF]

open access: yes, 2014
The aim this article a critical discursive analysis of the “management plan” genre of a public institution of higher education, from 2012 to 2015, located in southeast Brazil.
Baêta, Odemir Vieira   +2 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Training and Retaining Public Servants for the Future

open access: yesTransylvanian Review of Administrative Sciences
Demographic changes with an ageing popula­tion and declining birth rates, alongside economic challenges, have implications for the public service labour market.
Karen Johnston, Andrew Massey
doaj   +1 more source

A reforma da administração pública e a evolução do estado-providencia em Portugal: história recente

open access: yesLer História, 2020
Over the past three decades, the history of Portuguese public administration (PA) reforms have been mainly marked by the introduction of New Public Management (NPM) principles in public management.
César Madureira
doaj   +1 more source

The Impact of Strategic Planning on the Reform of Lebanese Public Administration [PDF]

open access: yesRevista de Management Comparat International, 2019
For Lebanon to reach its future obligations prior to the implementation of “Capital Investment Plan” or what we called “Cedar Project”, the need for strategy in Lebanese Public Administration reform is substantial. An efficient and effective mechanism to
Charbel El AMMAR
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Performance Management Systems Productivity in the Public Sector: Wither African Public Administration

open access: yesAfrica’s Public Service Delivery & Performance Review, 2014
Performance management has attracted a lot of debate in the recent past. It is a systematic effort to improve performance through an ongoing process of establishing desired outcomes, setting performance standards to improve performance and productivity ...
Jacob Olufemi Fatile
doaj   +1 more source

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