Results 61 to 70 of about 35,750,234 (281)
Africa’s Public Service Delivery & Performance Review, 2014 Performance management has attracted a lot of debate in the recent past. It is a systematic effort to improve performance through an ongoing process of establishing desired outcomes, setting performance standards to improve performance and productivity ...
Jacob Olufemi Fatile
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
From Bureaucracy to New Public Management: The Case Of The United Arab Emirates Federal Government
, 2017 The objective of this paper is to analyze and critically assess the evolution of the United Arab Emirates (UAE) federal administrative system from a traditional public administration system to a new public management one (or Reinventing Government ...
Mansour, Ahmed Mustafa
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
New Public Management – Public Policy for Institutional Reforms
Acta Economica et Turistica, 2021 The New Public Management model contains public policies for market-driven institutional reforms. Countries that applied this model are generally among the TOP 20 in global rankings concerning human development, human freedom, economic freedom, ease of ...
Daniel Hinšt
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Penjajagan Awal Penerapan 'New Public Management' dalam Administrasi Kabupaten
JSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2002 The popularity of New Public Management in the developed countries raises a question whether such a concept applicable in the Third World context. Relies on three focuses group discussion involving local bureaucrats, this article shows the desirability ...
Samodra Wibawa
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source