Results 61 to 70 of about 923,286 (230)
Twelve species of the genus Aphelenchoides were collected and identified based on morphological and morphometric characters from different regions in North, South and Western Iran. Among collected species i. e. A. centralis, A. cibolensis, A.
Yaser Adeldoost +3 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Chinese species of the genus Phanerotoma (Hymenoptera, Braconidae, Cheloninae) are revised. In total, 44 species are recognised, of which 24 are newly described: P. acclivirugata sp. nov., P. acuticlypealis sp. nov., P. aequidentata sp.
Wen-Juan Luo +4 more
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
New lichen records from Turkey
Three lichen species, namely Cladonia grayi G. Merr. ex Sandst., Pertusaria subventosa Malme var. subventosa, and Parmelia squarrosa Hale are reported as new to Turkey as a result of a lichenological survey in the Burdur region of the country. Descriptions are presented, including geographic distribution, substrate, chemistry, and comparisons with ...
Yazici, Kenan +2 more
openaire +6 more sources
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Wolfniana viridis sp. nov. is described and illustrated based on specimens collected in the municipality of Ipixuna (along Liberdade and Gregório rivers), state of Amazonas, Brazil. The new species can be distinguished from the type-species, W. limbatula
Rodney Ramiro Cavichioli +1 more
doaj +1 more source

