Results 41 to 50 of about 23,552,421 (303)

Economic and Social Aspects of the Space Sector Development Based on the Modified Structure–Conduct–Performance Framework

open access: yesWorld
Background: The global space economy has grown remarkably, witnessing a 10-fold increase in active satellites during the last 15 years. This growth was accompanied by both the increase in geopolitical tensions feeding huge investments (the New Space Race)
Michał Pietrzak
doaj   +1 more source

Anomalous Meltwater From Ice Sheets and Ice Shelves Is a Historical Forcing

open access: yesGeophysical Research Letters, 2023
Recent mass loss from ice sheets and ice shelves is now persistent and prolonged enough that it impacts downstream oceanographic conditions. To demonstrate this, we use an ensemble of coupled GISS‐E2.1‐G simulations forced with historical estimates of ...
Gavin. A. Schmidt   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Machine Learning Approach to Predict Radiation Effects in Microelectronic Components

open access: yesSensors
This paper presents an innovative technique, Advanced Predictor of Electrical Parameters, based on machine learning methods to predict the degradation of electronic components under the effects of radiation.
Fernando Morilla   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

New Jersey open space policy plan

open access: yes, 1968
This report suggests policies with respect to levels of governmental responsibility, standards, and location of open space to serve the needs of the people of the State at the ten million population level (or over the next 25 or 30 years).

core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Application of spectral analysis techniques to the intercomparison of aerosol data – Part 4: Synthesized analysis of multisensor satellite and ground-based AOD measurements using combined maximum covariance analysis [PDF]

open access: yesAtmospheric Measurement Techniques, 2014
In this paper, we introduce the usage of a newly developed spectral decomposition technique – combined maximum covariance analysis (CMCA) – in the spatiotemporal comparison of four satellite data sets and ground-based observations of aerosol optical ...
J. Li, B. E. Carlson, A. A. Lacis
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Submersible Space Training Suit Preliminary Test Results and Review

open access: yes
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Smith, Cameron, Tresch, Trent
core   +3 more sources

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