Results 61 to 70 of about 23,552,421 (303)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Modular and Highly Reliable COTS-Based Power Conditioning and Distribution Unit for Small Satellites

Aerospace
This paper presents a modular Power Conditioning and Distribution Unit (PCDU) designed for small satellites. The proposed system features a highly adaptable architecture capable of managing a total power throughput of up to 100 W, with specific limits ...
Cristian Torres Vergara, José Manuel Blanes Martínez, Ausiàs Garrigós Sirvent, David Marroquí Sempere, Pablo Casado Pérez, José Luis Lizan Mas   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Magnetospheric Multiscale Mission observations and non‐force free modeling of a flux transfer event immersed in a super‐Alfvénic flow

Geophysical Research Letters, 2016
We analyze plasma, magnetic field, and electric field data for a flux transfer event (FTE) to highlight improvements in our understanding of these transient reconnection signatures resulting from high‐resolution data.
C. J. Farrugia, B. Lavraud, R. B. Torbert, M. Argall, I. Kacem, W. Yu, L. Alm, J. Burch, C. T. Russell, J. Shuster, J. Dorelli, J. P. Eastwood, R. E. Ergun, S. Fuselier, D. Gershman, B. L. Giles, Y. V. Khotyaintsev, P. A. Lindqvist, H. Matsui, G. T. Marklund, T. D. Phan, K. Paulson, C. Pollock, R. J. Strangeway   +23 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Galactic Cosmic Radiation in the Interplanetary Space Through a Modern Secular Minimum

Space Weather, 2020
Recent solar conditions indicate a persistent decline in solar activity—possibly similar to the past solar grand minima. During such periods of low solar activity, the fluxes of galactic cosmic rays (GCRs) increase remarkably, presenting a hazard for ...
F. Rahmanifard, W. C. deWet, N. A. Schwadron, M. J. Owens, A. P. Jordan, J. K. Wilson, C. J. Joyce, H. E. Spence, C. W. Smith, L. W. Townsend   +9 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source