Results 91 to 100 of about 5,665,814 (317)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Revision of the Australian bee subgenus Leioproctus (Euryglossidia) Cockerell, 1910 (Hymenoptera: Colletidae: Neopasiphaeinae)

open access: yesRecords of the Australian Museum
The subgenus Leioproctus (Euryglossidia) is a large group of Australian Neopasiphaeine bees in need of revision. Forty-five new species are described, bringing the number of recognised names to 60.
Michael Batley
doaj   +1 more source

Stygocladius multisetosus gen. nov., sp. nov., a rheophilic element, inhabiting basaltic and karstic helocrenes in France and Algeria (Diptera: Chironomidae)

open access: yesFauna Norvegica, 2012
Diagnoses and descriptions of the adults and pupal exuviae of Stygocladius multisetosus gen. nov., sp. nov., are provided based primarily on male and female pharates collected in temporary basaltic and karstic helocrenes in southern France and Algeria ...
Joel Moubayed-Breil   +2 more
doaj   +1 more source

A new species of Cydistomyia (Diptera, Tabanidae) from Papua New Guinea [PDF]

open access: yes, 1999
A new species, Cydistomyia kamialiensis, is described from specimens collected in the Kamiali Wildlife Management Area of Morobe Province, Papua New ...
Goodwin, James T.
core  

New looks at and for Onespa, Buzyges, and Librita (Lepidoptera: Hesperiidae: Hesperiinae), with new combinations and descriptions of a new genus and six new species [PDF]

open access: yes, 2009
Thirteen species of skippers (six newly described; Lepidoptera: Hesperiidae: Hesperiinae: Hesperiini) from higher elevations of Mexico and Central America are reviewed.
Austin, George T., Warren, Andrew D.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

New data on the huntsman spiders (Araneae, Sparassidae) of China [PDF]

open access: yesBiodiversity Data Journal
Sparassidae Bertkau, 1872 is the tenth largest family of Araneae, with 11 genera and 288 species known in China.In the current paper, four newly-recorded species from China are provided: Heteropoda acris Korai & Jäger, 2024, Olios sericeus ...
Changhao Hu, He Zhang, Yang Zhong
doaj   +3 more sources

The Dynastinae (Coleoptera: Scarabaeidae) of the Cayman Islands (West Indies), with descriptions of Tomarus adoceteus, new species (Pentodontini) and Caymania nitidissima, new genus and species (Phileurini) [PDF]

open access: yes, 2010
The five genera and eight species of dynastine scarabs occurring in the Cayman Islands in the West Indies are reviewed. Two new, endemic species are described from Little Cayman, with supporting illustrations: Tomarus adoceteus Ratcliffe and Cave ...
Cave, Ronald D., Ratcliffe, Brett C.
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

New Species of Uredineae-XIII

open access: yesBulletin of the Torrey Botanical Club, 1911
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

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