Results 121 to 130 of about 23,539,549 (319)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Descriptions of four new species of Cryptolestes Ganglbauer : with a revised key to the New World species and notes on other species (Coleoptera: Laemophloeidae) [PDF]
, 2002 The following new species of Cryptolestes Ganglbauer are described and illustrated: Cryptolestes obesus Thomas, new species, Brazil; Cryptolestes turnbowi Thomas, new species, Honduras and Mexico; Cryptolestes inyoensis Thomas, new species, California ...
Thomas, Michael C.
core
Records of the Australian MuseumThe subgenus Leioproctus (Euryglossidia) is a large group of Australian Neopasiphaeine bees in need of revision. Forty-five new species are described, bringing the number of recognised names to 60.
Michael Batley
doaj +1 more source
Bulletin of the Torrey Botanical Club, 1907 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
European Journal of TaxonomyThe Neotropical genera Parasphen Enderlein, 1922 and Ptilosphen Enderlein, 1922 are revised. Parasphen rufipes (Fabricius, 1805) is given as a new combination, Parasphen frontalis Cresson, 1930 and Parasphen amazonicus ruficauda Curran, 1932 are treated
Stephen A. Marshall, Steven M. Paiero
doaj +1 more source
Fauna Norvegica, 2012 Diagnoses and descriptions of the adults and pupal exuviae of Stygocladius multisetosus gen. nov., sp. nov., are provided based primarily on male and female pharates collected in temporary basaltic and karstic helocrenes in southern France and Algeria ...
Joel Moubayed-Breil +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
New data on the huntsman spiders (Araneae, Sparassidae) of China [PDF]
Biodiversity Data JournalSparassidae Bertkau, 1872 is the tenth largest family of Araneae, with 11 genera and 288 species known in China.In the current paper, four newly-recorded species from China are provided: Heteropoda acris Korai & Jäger, 2024, Olios sericeus ...
Changhao Hu, He Zhang, Yang Zhong
doaj +3 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source