Results 111 to 120 of about 5,178,954 (288)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
1D models of the thermohydraulic systems supported by CFD results and measured data
In this paper is reported the way of simulation of thermohydraulic systems as whole real systems consisting of many parts. The crucial demand in our approach was to develop a software within the whole thermohydraulic system could be quickly designed and ...
Čibera Václav +2 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
JCA Eni ENEA Project: CSP & Thermal Storage
This project is framed inside a three-year-long cooperation between Eni and ENEA. It concerns the development of prototypes, technologies, innovative processes, feasibility studies, scenario analysis, exchanging skills, and know-how.
Raffaele Liberatore +9 more
doaj +1 more source
Visual Literacy and New Technologies [PDF]
This body of research addresses the connection between arts, identity and new technology, and investigates the impact of images on adolescent identities, the relationship between online modes of communication and cyber-bullying, the increasing ...
Bamford, Anne
core
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Harmony and Technology Enhanced Learning [PDF]
New technologies offer rich opportunities to support education in harmony. In this chapter we consider theoretical perspectives and underlying principles behind technologies for learning and teaching harmony.
Holland, Simon
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Driving tasks and new information technologies [PDF]
Fastenmeier, Wolfgang, Gstalter, Herbert
core +1 more source

