Results 101 to 110 of about 5,260,738 (315)

Progress of the Plasma Centerpost for the PROTO-SPHERA Spherical Tokamak

Energies, 2016
Plasma properties can be useful in a wide spectrum of applications. Experimental projects on controlled nuclear fusion are the most challenging of these applications and, at the same time, the best way to approach plasma science.
Alessandro Lampasi, Giuseppe Maffia, Franco Alladio, Luca Boncagni, Federica Causa, Edmondo Giovannozzi, Luigi Andrea Grosso, Alessandro Mancuso, Paolo Micozzi, Valerio Piergotti, Giuliano Rocchi, Alessandro Sibio, Benedetto Tilia, Vincenzo Zanza   +13 more
doaj   +1 more source

Training for New Technologies. Handwriting with New Technologies

Procedia - Social and Behavioral Sciences, 2014
AbstractIn the context of a digital age that covered all sectors of modern life, new technologies are suffering multiple interpretations, approaches and different uses. To pass through a stage of adult education means to relate to what is new, but also valuable and able to be used in different contexts.
Chicu, Smaranda Onofrei, Ţicău, Alina, Şoitu, Laurenţiu   +2 more
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Regulation of new technologies and new technologies in regulation

International Journal of Digital Law, 2020
O artigo trata das novas tecnologias e sua relação com o direito administrativo, especialmente no campo da regulação estatal. Inicialmente, apresentam-se as tecnologias por uma classificação setorial. Em seguida, abordam-se as tecnologias como objeto de estímulo, de demanda, de controle e de uso pela Administração Pública.
Thiago Marrara, Gustavo Gil Gasiola
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Design, assembly, alignment and application of a versatile, open-source, single-pixel microscope

Scientific Reports
Single-pixel microscopy (SPM) is an emerging imaging technique in which a sample is illuminated with a series of micro-structured light patterns, typically generated by a digital micromirror device (DMD).
Samuel I. Zapata-Valencia, Heberley Tobón-Maya, Luis Ordoñez, Andrea Farina, Jesús Lancis, Enrique Tajahuerce   +5 more
doaj   +1 more source

Blockchain technology into the logistics supply chain implementation effectiveness [PDF]

, 2018
Technologies currently have a tremendous impact on all spheres of economy, business and a state. They integrally change people’s conception of trade, property, and market entities interaction.
Britchenko, Igor, Cherniavska, Tetiana, Cherniavskyi, Bogdan   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

E-commerce technology adoption framework by New Zealand small to medium size enterprises [PDF]

, 2001
This paper attempts to highlight a framework for the adoption of electronic commerce (EC) technologies in New Zealand with specific interest in the small to medium-size enterprise (SME) sector of the economy.
Rashid, M.A.
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source