Results 51 to 60 of about 1,441,615 (268)
Communications BiologyThe efficient transport of proteins into the primary cilium is a crucial step for many signaling pathways. Dysfunction of this process can lead to the disruption of signaling cascades or cilium assembly, resulting in developmental disorders and cancer ...
S. M. Niedziółka +7 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Nature CommunicationsCreating and maintaining a favorable microenvironment for electrocatalytic CO2 reduction reaction (eCO2RR) is challenging due to the vigorous interactions with both gas and electrolyte solution during the electrocatalysis.
Ting Xu +15 more
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Review of Streptococcus salivarius BLIS K12 in the Prevention and Modulation of Viral Infections
Applied MicrobiologyThe discovery and application of bacteriocin-producing probiotics, such as Streptococcus salivarius K12 (BLIS K12), represent significant advances in the prevention and management of bacterial infections, particularly in the oral cavity and upper ...
John R. Tagg +2 more
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Method for emissivity measurement of semitransparent coatings at ambient temperature
Scientific Reports, 2017 Coatings deposited on a material surface are effective way of changing its surface properties. For increasing or decreasing radiation heat transfer, coatings with high or low emissivity are used.
Petra Honnerová +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Безопасность информационных технологий, 2013 At the descriptive level is considered the approach to the development of programs of training and retraining of the officials, authorized to organize the work in the area of licensed activity, connected with cryptographic means.
Alexander Vladimirovich Volgin +2 more
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Some perspectives of the innovation development in Ukraine: needs in new technologies and materials [PDF]
Marketing i Menedžment Innovacij, 2014 The aim of the article. The main aim of the article is to show what kind of technologies and materials Ukraine needs, if the country starts the innovation type of its economic growth. Particularly, the author paid attention to the idea that all direction
Sichkarenko Kyrylo Oleksiyovich
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