Results 41 to 50 of about 7,456 (191)

How many large camelids in the world? A synthetic analysis of the world camel demographic changes

Pastoralism, 2020
At world level, the current official number of large camelids cannot be determined exactly (it is estimated to be more than 35 million heads), and the role of camels in the livestock economy is highly variable.
B. Faye
doaj   +1 more source

Miniatures and Animism: The communicative role of Inka carved stone conopa [PDF]

, 2016
Andean offerings use miniaturisation and synecdoche to enact connections within a relational animism (where people, places and things participate in an interactive network), allowing the person preparing the offering to make material links between them ...
Sillar, B
core   +1 more source

Nucleotide diversity of functionally different groups of immune response genes in Old World camels based on newly annotated and reference-guided assemblies

BMC Genomics, 2020
Background Immune-response (IR) genes have an important role in the defense against highly variable pathogens, and therefore, diversity in these genomic regions is essential for species’ survival and adaptation.
Sara Lado, Jean P. Elbers, Mark F. Rogers, José Melo-Ferreira, Adiya Yadamsuren, Jukka Corander, Petr Horin, Pamela A. Burger   +7 more
doaj   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Evaluation of insulin secretion and action in New World camelids

American Journal of Veterinary Research, 2013
Abstract Objective—To measure and compare insulin secretion and sensitivity in healthy alpacas and llamas via glucose clamping techniques. Animals—8 llamas and 8 alpacas. Procedures—Hyperinsulinemic euglycemic clamping (HEC) and hyperglycemic clamping (HGC) were performed on each camelid in a crossover design with a minimum 48-hour washout period ...
Anna M, Firshman, Christopher K, Cebra, Barbara J, Schanbacher, Elizabeth R, Seaquist   +3 more
openaire   +2 more sources

Camelids and sustainable development [PDF]

, 2015
Face to the global changes and new climatic constraints, the camel farming is confronted to new challenges, first to contribute to the “livestock revolution” (for reaching the requirements of a growing human population), especially in remote places of ...
Faye, Bernard
core  

A mass sacrifice of children and camelids at the Huanchaquito-Las Llamas site, Moche Valley, Peru.

PLoS ONE, 2019
Here we report the results of excavation and interdisciplinary study of the largest child and camelid sacrifice known from the New World. Stratigraphy, associated artifacts, and radiocarbon dating indicate that it was a single mass killing of more than ...
Gabriel Prieto, John W Verano, Nicolas Goepfert, Douglas Kennett, Jeffrey Quilter, Steven LeBlanc, Lars Fehren-Schmitz, Jannine Forst, Mellisa Lund, Brittany Dement, Elise Dufour, Olivier Tombret, Melina Calmon, Davette Gadison, Khrystyne Tschinkel   +14 more
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

First report of anthelmintic resistance in Haemonchus contortus in alpacas in Australia [PDF]

, 2013
BACKGROUND: Parasitic nematodes can cause substantial clinical and subclinical problems in alpacas and anthelmintics are regularly used to control parasitic nematodes in alpacas.
Abdul Jabbar, Angus JD Campbell, Jennifer A Charles, Robin B Gasser   +3 more
core   +1 more source