Results 61 to 70 of about 602,273 (214)

The path to the G protein‐coupled receptor structural landscape: Major milestones and future directions

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel   +11 more
wiley   +1 more source

The steppe species of gastrointestinal nematodes of small ruminants, with a focus on Marshallagia: climate as a key determinant

open access: yesParasite, 2011
We intended to relate the geographic distribution of ruminant gastrointestinal nematodes in relation to steppe climate (and vegetation). Data are either from literature or from newly acquired/ available results.
Meradi S.   +3 more
doaj   +1 more source

Incorporating the Competencies of Evidence‐Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Building the skills and knowledge necessary to practice evidence‐based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the biomedical literature for evidence, critically appraising the evidence, and applying the evidence to make a ...
Virginia R. Fajt   +4 more
wiley   +1 more source

Self-Supervised Features Improve Open-World Learning [PDF]

open access: yesarXiv, 2021
This paper identifies the flaws in existing open-world learning approaches and attempts to provide a complete picture in the form of \textbf{True Open-World Learning}. We accomplish this by proposing a comprehensive generalize-able open-world learning protocol capable of evaluating various components of open-world learning in an operational setting. We
arxiv  

The Digestive System of New World Camelids - Common Digestive Diseases of Llamas [PDF]

open access: yes, 1988
Llamas (Lama glama) belong to a group of animals called South American or New World Camelids, which also includes the Guanaco (Lama guanicoe) , the Vicuna (Lama vicugna) and the Alpaca (Lama pacos). They are originally from South America, residing in the
Esteban, L. R., Thompson, J. R.
core   +2 more sources

Miniatures and Animism: The communicative role of Inka carved stone conopa [PDF]

open access: yes, 2016
Andean offerings use miniaturisation and synecdoche to enact connections within a relational animism (where people, places and things participate in an interactive network), allowing the person preparing the offering to make material links between them ...
Sillar, B
core   +1 more source

The Camel Adaptive Immune Receptors Repertoire as a Singular Example of Structural and Functional Genomics

open access: yesFrontiers in Genetics, 2019
The adaptive immune receptors repertoire is highly plastic, with its ability to produce antigen-binding molecules and select those with high affinity for their antigen.
Salvatrice Ciccarese   +10 more
doaj   +1 more source

Engineering and Structural Elucidation of a Sac7d‐Derived IgG Fc‐Specific Affitin and Its Application for the Light‐Controlled Affinity Purification of Antibodies

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl   +7 more
wiley   +1 more source

Unidentified Video Objects: A Benchmark for Dense, Open-World Segmentation [PDF]

open access: yesarXiv, 2021
Current state-of-the-art object detection and segmentation methods work well under the closed-world assumption. This closed-world setting assumes that the list of object categories is available during training and deployment. However, many real-world applications require detecting or segmenting novel objects, i.e., object categories never seen during ...
arxiv  

Invited review: Camel skin diseases survey in Morocco [PDF]

open access: yes, 2019
The present study aimed to collect data related to skin diseases in dromedary camels in the south of Morocco. As a whole, 168 herds from 9 provinces located in the south of Morocco have been prospected.
Bengoumi, Mohammed   +3 more
core  

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