Results 121 to 130 of about 90,270 (301)
Animal Models and Experimental Medicine, EarlyView.Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma +2 more
wiley +1 more source
The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart
Animal Models and Experimental Medicine, EarlyView.The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang +8 more
wiley +1 more source
Oxytocin structure and function in New World monkeys: from pharmacology to behavior. [PDF]
Integr Zool, 2018 Mustoe A, Taylor JH, French JA.
europepmc +1 more source
Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva
Advanced NanoBiomed Research, EarlyView.A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang +8 more
wiley +1 more source
Manipulating Ferroelectricity Without Electrical Bias: A Perspective
Advanced Physics Research, EarlyView.Alternatives to electrical bias to control ferroelectric polarization are highly desired for the development of ferroelectric‐based applications. The polarizing role of chemically engineered surfaces, the impact of chemical substitution and mechanical pressure, and light‐induced effects on the final polarization state are highlighted in this short ...
Bixin Yan +3 more
wiley +1 more source
Submillimeter fMRI reveals a layout of dorsal visual cortex in macaques, remarkably similar to New World monkeys. [PDF]
Proc Natl Acad Sci U S A, 2019 Zhu Q, Vanduffel W.
europepmc +1 more source
The Anatomical Record, EarlyView.Abstract With the development of dental microwear texture analysis (DMTA), there has been an increasing application of DMTA for dietary estimation in extant and fossil reptiles, including dinosaurs. While numerous feeding experiments exist for herbivorous mammals, knowledge remains limited for carnivorous reptiles. This study aimed to qualitatively and
K. Usami, M. O. Kubo
wiley +1 more source