Results 31 to 40 of about 10,524,912 (302)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Postdramatic Theatre and Postdramatic Performance
Revista Brasileira de Estudos da Presença, 2015 Beginning with the concept of a postdramatic theatre as articulated by the German theorist Hans-Thies Lehmann, this essay considers the recent work of several major international directors – Ivo van Hove, Punchdrunk, Signa and others – as examples of ...
Marvin Carlson (The City University of New York – New York, United States of America)
doaj
Invoice from Harkness Boyd [PDF]
, 1897 https://digitalcommons.salve.edu/goelet-new-york/1098/thumbnail ...
Boyd, Harkness
core +22 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Receipt from Benj. Gillespie to P. McCormick and Receipt from Peter McCormick to Ogden Goelet [PDF]
, 1897 https://digitalcommons.salve.edu/goelet-new-york/1013/thumbnail ...
Gillespie, Benjamin, McCormick, Peter
core +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Columbia Social Work Review, 2016 Homelessness continues to be a persistent and highly visible public health issue in New York City. New York/New York III, the current initiative that aims to expand supportive housing services for New York City’s chronically homeless mentally ill ...
LeeAnn Shan, Matt Sandler
doaj +1 more source
, 1898 https://digitalcommons.salve.edu/goelet-new-york/1336/thumbnail ...
Firth, T.
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Receipt from Montgomery Maze $41.03 [PDF]
, 1897 https://digitalcommons.salve.edu/goelet-new-york/1252/thumbnail ...
Maze, Montgomery
core +3 more sources