Results 31 to 40 of about 2,704,572 (279)

Addressing the Homelessness Crisis in New York City: Increasing Accessibility for Persons With Severe and Persistent Mental Illness

Columbia Social Work Review, 2016
Homelessness continues to be a persistent and highly visible public health issue in New York City. New York/New York III, the current initiative that aims to expand supportive housing services for New York City’s chronically homeless mentally ill ...
LeeAnn Shan, Matt Sandler
doaj   +1 more source

NEW YORK. [PDF]

The Lancet, 1885
n ...
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Journal of the New York Botanical Garden

, 1934
Vols. for 1933-1941, 1945 include the Annual report of the director, 1933-1940, 1944 (previously published in its Bulletin). Indexes: Vols. 1-15, 1900-1914, issued as v. 15, no. 180; Vols. 16-30, 1915-1929, issued as v. 30, no. 360.

core   +2 more sources

Journal of the New York Botanical Garden

, 1950
Vols. for 1933-1941, 1945 include the Annual report of the director, 1933-1940, 1944 (previously published in its Bulletin). Indexes: Vols. 1-15, 1900-1914, issued as v. 15, no. 180; Vols. 16-30, 1915-1929, issued as v. 30, no. 360.

core   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Journal of the New York Botanical Garden

, 1931
Vols. for 1933-1941, 1945 include the Annual report of the director, 1933-1940, 1944 (previously published in its Bulletin). Indexes: Vols. 1-15, 1900-1914, issued as v. 15, no. 180; Vols. 16-30, 1915-1929, issued as v. 30, no. 360.

core   +2 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Journal of the New York Botanical Garden

, 1939
Vols. for 1933-1941, 1945 include the Annual report of the director, 1933-1940, 1944 (previously published in its Bulletin). Indexes: Vols. 1-15, 1900-1914, issued as v. 15, no. 180; Vols. 16-30, 1915-1929, issued as v. 30, no. 360.

core   +3 more sources