Results 31 to 40 of about 305,896 (139)

Asthma control with ICS-formoterol reliever versus maintenance ICS and SABA reliever therapy: a post hoc analysis of two randomised controlled trials

BMJ Open Respiratory Research, 2022
Background In randomised controlled trials, as-needed inhaled corticosteroid (ICS)-formoterol reliever therapy reduces severe exacerbation risk compared with maintenance ICS plus short-acting beta2-agonist (SABA) reliever in adolescent and adult asthma ...
, James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite, Ian Pavord, Jenny Sparks, Lee Hatter, Helen K Reddel, Robert J Hancox, Mark Holliday, Andrew Corin, Daniela Hall, Claire Houghton, Saras Mane, John Martindale, Karen Oldfield, Donah Sabbagh, Alexandra Vohlidkova, Alberto Papi, Allie Eathorne, Pepa Bruce   +21 more
doaj   +1 more source

Genetic Variation in Drought-Tolerance Traits and Their Relationships to Growth in Pinus radiata D. Don Under Water Stress

Frontiers in Plant Science, 2022
The selection of drought-tolerant genotypes is globally recognized as an effective strategy to maintain the growth and survival of commercial tree species exposed to future drought periods.
Ahmed Ismael, Ahmed Ismael, Jianming Xue, Dean Francis Meason, Jaroslav Klápště, Marta Gallart, Yongjun Li, Yongjun Li, Pierre Bellè, Mireia Gomez-Gallego, Mireia Gomez-Gallego, Ki-Taurangi Bradford, Emily Telfer, Heidi Dungey   +13 more
doaj   +1 more source

Genomic analysis of the population structure of Paenibacillus larvae in New Zealand

Frontiers in Microbiology, 2023
New Zealand is a remote country in the South Pacific Ocean. The isolation and relatively late arrival of humans into New Zealand has meant there is a recorded history of the introduction of domestic species. Honey bees (Apis mellifera) were introduced to
Barbara M. Binney, Hayley Pragert, Jonathan Foxwell, Edna Gias, Meredith L. Birrell, Bernard J. Phiri, Oliver Quinn, Michael Taylor, Hye Jeong Ha, Richard J. Hall   +9 more
doaj   +1 more source

Multi-model ensemble forecasts of sea surface temperatures and marine heatwaves for Aotearoa New Zealand

Frontiers in Marine Science
Marine heatwaves (MHWs) adversely impact Aotearoa New Zealand’s marine ecosystems and pose challenges for resource management. In this study, we evaluate forecast skill of monthly MHWs and sea surface temperature (SST) anomalies using a multi-model ...
Rafael Santana, Rafael Santana, Neelesh Rampal, Nicolas Fauchereau, Hamish Lewis, Hamish Lewis, François Thoral, François Thoral, Peter B. Gibson, Niall Broekhuizen   +9 more
doaj   +1 more source

Automated oxygen titration with non-invasive ventilation in hypoxaemic adults with cardiorespiratory disease: a randomised cross-over trial

BMJ Open Respiratory Research
Background Closed-loop oxygen control systems automatically adjust the fraction of inspired oxygen (FiO2) to maintain oxygen saturation (SpO2) within a predetermined target range.
Ruth Semprini, Alex Semprini, Mark Weatherall, Richard Beasley, Allie Eathorne, Melissa Black, Louis Kirton, Stacey Kung, Georgina Bird   +8 more
doaj   +1 more source

Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Recent work suggests that amyloid beta (Aβ) positron emission tomography (PET) tracer uptake shortly after injection (“early phase”) reflects brain metabolism and perfusion.
William W. T. Aye, Megan R. Stark, Kyla‐Louise Horne, Leslie Livingston, Sophie Grenfell, Daniel J. Myall, Toni L. Pitcher, Mustafa M. Almuqbel, Ross J. Keenan, Wassilios G. Meissner, John C. Dalrymple‐Alford, Tim J. Anderson, Campbell Le Heron, Tracy R. Melzer   +13 more
doaj   +1 more source

Protocol for the INFORM ASTHMA Trial: budesonide–formoterol reliever in adults with asthma on maintenance inhaled corticosteroid

ERJ Open Research
Background International asthma guidelines recommend inhaled corticosteroid (ICS)/formoterol in preference to short-acting β2-agonist (SABA) reliever-based regimens as reliever therapy in adults and adolescents of all asthma severities.
Jonathan Noble, Orlagh Bean, Pepa Bruce, Melissa Black, Ross Sayers, Ryan Cullen, Bianca Black, Mark Holliday, Louis Kirton, Blake Perry, Allie Eathorne, Ian Pavord, Mark Weatherall, Richard Beasley   +13 more
doaj   +1 more source

Tolerability of Nasal Delivery of Humidified and Warmed Air at Different Temperatures: A Randomised Double-Blind Pilot Study

Pulmonary Medicine, 2016
Objectives. Delivery of warmed, humidified air via nasal high flow therapy could potentially reduce replication of temperature-sensitive viruses in the upper respiratory tract.
Susan Bibby, Sumeet Reddy, Terrianne Cripps, Steve McKinstry, Mark Weatherall, Richard Beasley, Janine Pilcher   +6 more
doaj   +1 more source

Patterns of asthma medication use and hospital discharges in New Zealand

Journal of Allergy and Clinical Immunology: Global
Background: In New Zealand a progressive increase in budesonide/formoterol dispensing, accompanied by a reduction in dispensing of short-acting β2-agonists (SABAs), inhaled corticosteroids (ICSs), and other ICS/long-acting β2-agonists (ICSs/LABAs ...
Jonathan Noble, MBBS, Lee Hatter, MBBS, Allie Eathorne, BSc, Thomas Hills, DPhil, Orlagh Bean, MBBS, Pepa Bruce, MBBS, Mark Weatherall, FRACP, Richard Beasley, DSc   +7 more
doaj   +1 more source

Marker Selection in Multivariate Genomic Prediction Improves Accuracy of Low Heritability Traits

Frontiers in Genetics, 2020
Multivariate analysis using mixed models allows for the exploration of genetic correlations between traits. Additionally, the transition to a genomic based approach is simplified by substituting classic pedigrees with a marker-based relationship matrix ...
Jaroslav Klápště, Heidi S. Dungey, Emily J. Telfer, Mari Suontama, Mari Suontama, Natalie J. Graham, Yongjun Li, Yongjun Li, Russell McKinley   +8 more
doaj   +1 more source