Results 71 to 80 of about 1,644,009 (334)

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

open access: yesAdvanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin   +14 more
wiley   +1 more source

Developing Successful Breeding Programs for New Zealand Aquaculture: A Perspective on Progress and Future Genomic Opportunities

open access: yesFrontiers in Genetics, 2019
Over the past 40 years New Zealand (NZ) aquaculture has grown into a significant primary industry. Tonnage is small on a global scale, but the industry has built an international reputation for the supply of high quality seafood to many overseas markets.
Jane E. Symonds   +10 more
doaj   +1 more source

He hauā Māori: findings from the 2013 disability survey [PDF]

open access: yes
A new report from Statistics New Zealand shows the importance of collecting good information about the one in four Māori who are disabled. He hauā Māori: findings from the 2013 disability survey shows that while many disabled Māori enjoy good levels of ...
Statistics New Zealand
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Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue   +13 more
wiley   +1 more source

Phytohormone and Putative Defense Gene Expression Differentiates the Response of ‘Hayward’ Kiwifruit to Psa and Pfm Infections

open access: yesFrontiers in Plant Science, 2017
Pseudomonas syringae pv. actinidiae (Psa) and Pseudomonas syringae pv. actinidifoliorum (Pfm) are closely related pathovars infecting kiwifruit, but Psa is considered one of the most important global pathogens, whereas Pfm is not.
Kirstin V. Wurms   +9 more
doaj   +1 more source

Greenhouse Gas Stabilisation: Principles to Guide the Formulation of Possible Targets and Policies and Measures [PDF]

open access: yes
The Ad Hoc Group on the Berlin Mandate at its fourth session requested the Secretariat to compile proposals relating to the treatment of quantified emission limitation and reduction objectives (QELROs) and policies and measures. This paper focuses on the
the New Zealand Delegation (1996)
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TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang   +15 more
wiley   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

open access: yesAdvanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong   +12 more
wiley   +1 more source

New Zealand

open access: yesIMF Staff Country Reports, 2019
New Zealand’s expansion lost momentum in 2017-18, as some key drivers started to weaken. Despite the long expansion, inflation remains weak, reflecting imported disinflation as well as strong net inward migration, which has boosted labor supply.
openaire   +3 more sources

Disability support services strategic plan 2014 to 2018 [PDF]

open access: yes
The Ministry of Health’s Disability Support Services (DSS) group has developed a four-year Strategic Plan for 2014 to 2018. Summary The plan sets out the vision for Disability Support Services – that disabled people and their families are ...
Ministry of Health (New Zealand)
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