Results 161 to 170 of about 524,540 (290)

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

Advanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang, Xiao Li, Shuyue Lei, Qingqing Li, Yi Zhang, Zhizhen Hui, Jinjin Ren, Xuelian Yang, Xiaoqian Yang, Chunlan Feng, Yousheng Xu, Dongxin Zhao, Wei Tang   +12 more
wiley   +1 more source

Essential newborn care practices and determinants in Ethiopia: a multilevel analysis of national survey data. [PDF]

BMJ Open
Mekonnen TS, Delie AM, Hailu M, Mehari MG, Bizuneh GK, Mengistie BA.   +5 more
europepmc   +1 more source

Chemotactic and Bactericidal Capacities of Human Newborn Monocytes [PDF]

, 1976
R Kretschmer, Prudence B. Stewardson, Cynthia K. Papierniak, Samuel P. Gotoff   +3 more
openalex   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Primary health care networks and impacts in low- and middle-income countries: a systematic review. [PDF]

Health Policy Plan
Gadeka DD, Aryeetey GC, Bour H, Okudzeto H, Addo P, de Siqueira Filha NT, Ebenso B, Elsey H, Agyepong IA.   +8 more
europepmc   +1 more source

Acylated Ghrelin, Growth Hormone and IGF-1 Levels in the Cord Blood of Small for Gestational Age Newborns [PDF]

, 2016
Nastaran Khosravi, Farhad Abolhasan Choobdar, Nasrin Khalesi, Arash Bordbar, Bagher Larijani, Zahra Arab, Mitra Nourbakhsh   +6 more
openalex   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Newborn Blood Smear - 12

, 2014
Marion Fraser
openalex   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Timing Routines With Patience: A Focused Ethnography on Newborn Breastfeeding in Hospitals. [PDF]

Matern Child Nutr
Frandsen AL, Rytter MJH, Haslund-Thomsen H, Broberg L, Schiøtz M, Beck M.   +5 more
europepmc   +1 more source