Results 51 to 60 of about 510,747 (317)

STUDY PROTOCOL: Improving newborn survival in rural southern Tanzania: a cluster-randomised trial to evaluate the impact of a scaleable package of interventions at community level with health system strengthening [PDF]

Child mortality has declined substantially in many countries including Tanzania, but newborn mortality remains high and around 3 million babies die every year in the first 28 days of life.
Marchant, T, Schellenberg, D, Cousens, S, Shamba, D, Borghi, J, Mkumbo, E, Hamisi, Y, Mshinda, H, Tanner, M, Hanson, C, Manzi, F, Penfold, S, Jaribu, J   +12 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Initial supplementary oxygen concentration for moderate-late preterm infants receiving respiratory support in the delivery room: statistical analysis plan for the multicenter, cluster-randomized crossover AIROPLANE Trial

Trials
Background Moderate-late preterm infants born at 32–35 completed weeks’ gestation constitute a large proportion of all preterm births (
Stacey Peart, Brett J. Manley, Cecilia Moore, Jeanie L. Y. Cheong, Ju Lee Oei, Li Huang, Peter G. Davis, Louise S. Owen, Anneke Grobler   +8 more
doaj   +1 more source

Williams-Beuren Syndrome and Congenital Lobar Emphysema: Uncommon Association with Common Pathology?

Case Reports in Pediatrics, 2017
Introduction. Congenital lobar emphysema (CLE) and Williams-Beuren Syndrome are two rare conditions that have only been reported together in a single case study. Case Presentation.
Timothy Andrew Walsh, Krishna Revanna Gopagondanahalli, Atul Malhotra   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Computer-assisted analysis of pleural and subpleural lung ultrasound correlates with oxygenation in preterm infants

Scientific Reports
Lung ultrasound (LUS) is increasingly used in neonatal intensive care, however visual scoring of LUS images remains subjective. Quantitative LUS (Q-LUS) is objective and whilst it detects small lung aeration changes in preterm animals, human data are ...
Selina K. X Zhang, Gillian W. C Foo, Sheryle R Rogerson, Niranjan Abraham, Penny Kee, Amir Zayegh, David G Tingay, Peter G Davis, Brett J Manley, Arun Sett   +9 more
doaj   +1 more source

Assessment of Quality of Life for Women Undergoing in Vitro [PDF]

Egyptian Journal of Health Care, 2016
AIM: To assess the quality of life for women undergoing in vitro fertilization. SETTING:The study was conducted at Hawaa private center at Benha city. DESIGN:A descriptive designwas used.
Eman Mohammed Abd-Elhakam, Amel Ahmed Hassan, Nadia Mohammed Fahmy, Amany Fikry Ali   +3 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Understanding cause of stillbirth: a prospective observational multi-country study from sub-Saharan Africa

BMC Pregnancy and Childbirth, 2019
Background Every year, an estimated 2.6 million stillbirths occur worldwide, with up to 98% occurring in low- and middle-income countries (LMIC). There is a paucity of primary data on cause of stillbirth from LMIC, and particularly from sub-Saharan ...
Mamuda Aminu, Sarah Bar-Zeev, Sarah White, Matthews Mathai, Nynke van den Broek   +4 more
doaj   +1 more source