Results 61 to 70 of about 1,389,521 (207)

Involvement of Adult Hippocampal Neurogenesis in Learning and Forgetting

Neural Plasticity, 2015
Adult hippocampal neurogenesis is a process involving the continuous generation of newborn neurons in the hippocampus of adult animals. Mounting evidence has suggested that hippocampal neurogenesis contributes to some forms of hippocampus-dependent ...
Suk-yu Yau, Ang Li, Kwok-Fai So
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Other title: Financial Review

, 2010
application/pdf; "December 13-14, 2010."; Includes bibliographical references."A Newborn Screening Financial Review Team...met with selected staff members of the newborn screening program of the Kansas Department of Health and Environment (
National Newborn Screening & Genetics Resource Center (U.S.)
core   +1 more source

Clinical trial results of an associated vaccine against cattle clostridiosis and escherichiosis [PDF]

BIO Web of Conferences
In veterinary practice, gastrointestinal diseases of newborn calves, caused by the association of pathogenic bacteria, in particular Clostridium perfringens and Escherichia coli, are often observed.
Spiridonov Anton, Spiridonov Gennady, Makhmutov Aidar, Kosarev Maksim, Gilmutdinov Rustam, Evstifeev Vitaly, Dupleva Liliya, Plotnikova Edie, Khuramshina Milyausha, Nasertdinov Dinar   +9 more
doaj   +1 more source

The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Development of the nervous system in human and most animals is continued after the birth. Critical role of this period in generation and specialization of the neuronal circuits is confirmed in numerous studies.
Masoud Naseri, Abbas Parham, Ali Moghimi
doaj   +1 more source

Neonatal resuscitation and immediate newborn assessment and stimulation for the prevention of neonatal deaths: a systematic review, meta-analysis and Delphi estimation of mortality effect. [PDF]

, 2011
BACKGROUND: Of 136 million babies born annually, around 10 million require assistance to breathe. Each year 814,000 neonatal deaths result from intrapartum-related events in term babies (previously "birth asphyxia") and 1.03 million from complications of
Carlo, Waldemar A, Bhutta Zulfiqar A, Darmstadt Gary L, Zulfiqar A Bhutta, Lawn, Joy E, Stephen N Wall, Gary L Darmstadt, Gill Christopher, Wall, Stephen N, Lawn, Joy E., Wall, Stephen N., Lawn Joy E, Joy E Lawn, Darmstadt, Gary L, Niermeyer Susan, Cousens Simon, Simon Cousens, William J Keenan, Lee, Anne CC, Gill, Christopher, Bhutta, Zulfiqar Ahmed, Lee Anne CC, Keenan, William J., Cousens, Simon, Susan Niermeyer, Keenan William J, Darmstadt, Gary L., Wall Stephen N, Bhutta, Zulfiqar A, Keenan, William J, Christopher Gill, Carlo, Waldemar A., Anne CC Lee, Carlo Waldemar A, Niermeyer, Susan, Lee, Anne C. C., Waldemar A Carlo   +36 more
core   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Aggregative properties of red blood cells platelets in young cattle in the first 10 days of life

RUDN Journal of Ecology and Life Safety, 2014
Objective: to establish features erythrocyte and platelet at healthy calfs in a phase newborn. The animals every day during the newborn phase determined aggregation cells using light microscopy and Visual mikrometod aggregation platelets. The results may
T A Belova, S Y Zavalishina, O V Nagornaya, I N Medvedev   +3 more
doaj  

Measuring Blood Plasma Glutamine Levels Using a Nanopore‐Based Sensor

Advanced Healthcare Materials, EarlyView.
Glutamine (GLN) is a biomarker useful for predicting toxic ammonia accumulation. Here, we used a biosensor based on the Cytolysin A (ClyA) nanopore coupled with the GLN‐specific protein substrate‐binding domain 2 (SBD2) to demonstrate real‐time measurement of GLN in blood plasma, highlighting the potential for future point‐of‐care applications ...
Sofia B. Relvas, Iris M. Kormelink, Sandra Michel‐Souzy, Florian L. R. Lucas, Nieck J. van der Heide, Hans R. Waterham, Ramon Versteeg, Judith Jans, Loes I. Segerink, Carsten Wloka   +9 more
wiley   +1 more source

Social modulation of the daily activity rhythm in a solitary subterranean rodent, the tuco-tuco (Ctenomys sp)

Sleep Science, 2016
South American subterranean rodents are mainly described as solitary and mutual synchronization was never observed among individuals maintained together in laboratory.
Barbara Mizumo Tomotani, Juan Pablo Amaya, Gisele Akemi Oda, Veronica Sandra Valentinuzzi   +3 more
doaj   +1 more source