Results 151 to 160 of about 220,107 (299)

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Genomic Newborn Screening: Verdict From an Australian Citizens' Jury. [PDF]

Med J Aust
Aquino YSJ, Scarfe J, Popic D, Carolan L, Degeling C, Prokopovich K, Otlowski MFA, Singh S, Fabrianesi B, Bhattacharya K, Jones K, Newson AJ, Shih P, Bennetts B, Frost E, Stark ZL, Nowak K, Healy L, Norris S, Carter SM.   +19 more
europepmc   +1 more source

Newborn Hearing Screening [PDF]

Journal of Midwifery & Women's Health, 2016
openaire   +2 more sources

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

The History of and Advances in Newborn Screening: Where Do We Stand? [PDF]

Genes (Basel)
Anderson S, Velinov M.
europepmc   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source

Newborn Screening in Fabry Disease. [PDF]

Int J Mol Sci
Olszewska M, Schwermer K, Pawlaczyk K.
europepmc   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Current Status of Newborn Screening in Southeastern and Central Europe. [PDF]

Int J Neonatal Screen
Požun N, Perko D, Anastasovska V, Barić I, Baša M, Battelino T, Bilandžija I, Brincat I, Brkušanin M, Djordević M, Dimova I, Drole Torkar A, Fumić K, Gladun S, Girginoudis P, Szatmári I, Kavečan I, Katanić J, Kotori V, Marić N, Martić J, Manđarelo O, Milenković T, Mlinarič M, Moldovanu F, Nanu M, Monostori P, Modeva I, Opančina B, Platis D, Raičević M, Remec ŽI, Repič Lampret B, Savov A, Skouma A, Sovtić A, Stoeva I, Toromanović A, Trampuž D, Usurelu N, Višekruna J, Vogazianos M, Zeyda M, Žerjav Tanšek M, Grošelj U.   +44 more
europepmc   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source