Results 111 to 120 of about 849,858 (379)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Early influence of auditory stimuli on upper-limb movements in young human infants: an overview

open access: yesFrontiers in Psychology, 2014
Given that the auditory system is rather well developed at the end of the third trimester of pregnancy, it is likely that couplings between acoustics and motor activity can be integrated as early as at the beginning of postnatal life.
Priscilla Augusta Monteiro Ferronato   +3 more
doaj   +1 more source

Epidemiologic aspects of neural tube defects in South East Iran [PDF]

open access: yes, 2006
Objectives: To investigate the rate of neural tube defects (NTDs) and their relation to gender, maternal age, consanguineous marriage, season, and drug consumption in Birjand, Iran.
Afshar, M., Farhud, D., Golalipour, M.J.
core  

Trends and determinants of newborn mortality in Kyrgyzstan: a Countdown country case study [PDF]

open access: gold, 2020
Mahdis Kamali   +12 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

Respiratory distress in newborns: current state of the problem

open access: yesВестник анестезиологии и реаниматологии
Introduction. Respiratory distress of newborns is one of the most common causes of complications, irreversible damage to the central nervous system and deaths in the neonatal period.The objective was to analyze the current features of epidemiology, risk ...
D. O. Ivanov   +2 more
doaj   +1 more source

Advanced Design for Weakly Coupled Resonators by Automatic Active Optimization

open access: yesAdvanced Materials Technologies, EarlyView.
An Automatic Active Optimization (AAO) strategy integrates machine learning predictors and genetic algorithms in a closed‐loop workflow. By iteratively expanding its dataset with new discoveries, AAO overcomes the limits of conventional methods. This approach finds superior microstructural designs beyond the initial sample space. We demonstrate this on
Wei Yue   +8 more
wiley   +1 more source

Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro [PDF]

open access: yes, 2018
Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a ...
Borriello, Francesco   +7 more
core   +1 more source

Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring

open access: yesAdvanced Materials Technologies, EarlyView.
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim   +8 more
wiley   +1 more source

Neurological outcomes in children undergoing multi-organ syndrome insufficiency in the neonatal period

open access: yesЛечащий Врач, 2021
Clinical and pathogenic role of undergoing multi-organ insufficiency syndrome (MOIS) in neonatal period in neurological outcome formation in in children was studied. 85 children who underwent MOIS in neonatal period, were examined. In the neonatal period,
O. K. Kirilochev   +2 more
doaj  

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