Results 51 to 60 of about 255,153 (264)

Psychological Impact of the COVID-19 Pandemic on Pregnant Women

Frontiers in Pediatrics, 2022
ObjectiveThe aim of this study is to assess the impact of the COVID-19 pandemic on mental health, type of delivery, and neonatal feeding of pregnant women with or without SARS-CoV-2 infection during gestation.Study DesignThe study was conducted online ...
Danilo Buonsenso, Danilo Buonsenso, Danilo Buonsenso, Walter Malorni, Arianna Turriziani Colonna, Sofia Morini, Martina Sbarbati, Alessandro Solipaca, Antonio Di Mauro, Brigida Carducci, Antonio Lanzone, Umberto Moscato, Simonetta Costa, Giovanni Vento, Piero Valentini, Piero Valentini, Piero Valentini   +16 more
doaj   +1 more source

Common Ethical Dilemmas Encountered in the Management of HIV-Infected Women and Newborns

, 1996
The clinical management of the HIV-infected pregnant woman and newborns involves multifaceted ethical challenges. We have argued that rights-based approaches, based on a civil rights model, are not adequate to clinically address these challenges. We have
Chervenak, Frank A., McCullough, Laurence B.   +1 more
core   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Early postnatal care uptake and its associated factors following childbirth in East Africa—a Bayesian hierarchical modeling approach

Frontiers in Public Health
BackgroundThe postnatal period is a critical period for both mothers and their newborns for their health. Lack of early postnatal care (PNC) services during a 2-day period is a life-threatening situation for both the mother and the babies.
Bewuketu Terefe, Dejen Kahsay Asgedom, Fetlework Gubena Arage, Setognal Birara Aychiluhm, Tadesse Awoke Ayele   +4 more
doaj   +1 more source

Proximate Personhood as a Standard Making Difficult Treatment Decisions: Imperiled Newborns as a Case Study

, 1992
...The standard of personhood is gaining increased attention and prominence. The essential claim is that only individuals with capacities for significant cerebral functioning possess a morally unique claim to existence.
Walters, James W.
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Newborn screening for primary congenital hypothyroidism: past, present and future

European Thyroid Journal
This manuscript reviews the evolution of newborn screening for primary congenital hypothyroidism (CH) and explores future strategies to enhance diagnostic accuracy.
Francisca Grob, Samantha Lain, Antonella Olivieri   +2 more
doaj   +1 more source

Syndrome of Jaundice in Newborns: Approaches to Therapy

Zdorovʹe Rebenka, 2014
The paper presents the mechanisms of hyperbilirubinemia syndrome development in newborns, its clinical and laboratory manifestations and treatment modes. The action of domestic preparation of ursodeoxycholic acid, Ukrliv suspension, is considered.
Ye.I. Yulish
doaj   +1 more source