Results 111 to 120 of about 608,200 (278)

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Treosulfan–fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study

British Journal of Haematology, EarlyView.
Summary Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for severe combined immunodeficiency (SCID). Conditioning improves donor engraftment and freedom from immunoglobulin replacement (IgR) but increases the risks of acute and late toxicity. Treosulfan, a reduced toxicity alkylating agent, has emerged as an alternative
Su Han Lum, Sinéad Greener, Irum Latif Memon, Persis Amrolia, Zohreh Nademi, Robert Chiesa, Juliana Silva, Helen Young, Stephen Owens, Eleri Williams, Khuen Foong Ng, Terry Flood, Andrew R Gennery, Sophie Hambleton, Kanchan Rao, Mary Slatter   +15 more
wiley   +1 more source

Serological monitoring of avian influenza and Newcastle disease in the Russian Federation in 2019

Ветеринария сегодня, 2020
More than 30,000 samples of blood serum from domestic, wild and synanthropic birds from 50 regions of the Russian Federation were submitted to the FGBI “ARRIAH” (Vladimir) Reference Laboratory for Avian Viral Diseases to be tested for avian influenza and
M. A. Volkova, I. A. Chvala, O. S. Osipova, M. A. Kulagina, D. B. Andreychuk, I. A. Chvala   +5 more
doaj   +1 more source

Multiplex evaluation of influenza neutralizing antibodies with potential applicability to in-field serological studies [PDF]

, 2014
The increased number of outbreaks of H5 and H7 LPAI and HPAI viruses in poultry has major public and animal health implications. The continuous rapid evolution of these subtypes and the emergence of new variants influence the ability to undertake ...
Cattoli, G., Cattoli, G., Molesti, E., Molesti, E., Rahman, R., Rahman, R., Temperton, N.J., Temperton, N.J., Terregino, C., Terregino, C., Wright, E., Wright, E.   +11 more
core   +6 more sources

New real time and conventional RT-PCRs for updated molecular diagnosis of infectious bronchitis virus infection (IBV) in chickens in Egypt associated with frequent co-infections with avian influenza and Newcastle Disease viruses

Journal of Virological Methods, 2017
Highlights • Development of molecular diagnostic tools for infectious bronchitis virus (IBV).• Segregation of the IBV Egyptian variant II into two phylogroups detected.• Frequent co-infections with IBV, avian influenza and Newcastle disease observed.
M. Naguib, M. El-kady, D. Lüschow, Kareem E Hassan, A. Arafa, A. EL-ZANATY, Mohamed K. Hassan, H. Hafez, C. Grund, T. Harder   +9 more
semanticscholar   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Serological Survey of the Newcastle Disease and Infectious Bursal Disease in Local Ducks and Local Guinea Fowls in Jos, Plateau State, Nigeria

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2004
A serological survey was conducted to determine the prevalence of Newcastle disease (ND) and infectious bursal disease (IBD) antibodies in local ducks and local guinea fowls brought from different locations within Plateau State and neighboring areas to ...
H. M. Mai, O. D. Ogunsola, O. L. Obasi
doaj   +1 more source

SCREENING FOR HEPATITIS C Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified [PDF]

, 2015
This is the peer reviewed published version of the following article: Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified, which has been published in final form at ...
Bhagani, S, Foster, GR, Gore, C, Hudson, M, Moss, P, Ryder, S, Ustianowski, A   +6 more
core   +1 more source

Newcastle Disease Virus as a Vaccine Vector for Development of Human and Veterinary Vaccines

Viruses, 2016
Viral vaccine vectors have shown to be effective in inducing a robust immune response against the vaccine antigen. Newcastle disease virus (NDV), an avian paramyxovirus, is a promising vaccine vector against human and veterinary pathogens.
Shin-Hee Kim, S. Samal
semanticscholar   +1 more source

Black Fugitivity in the Sporting Workplace: The Story of Eniola Aluko

Gender, Work &Organization, EarlyView.
ABSTRACT Being a Black fugitive involves constant movement: to find and cultivate spaces of safety and hope. In this paper, I curate a sporting archive about the UK Black women's elite football player Eniola Aluko to read her as a Black fugitive. I demonstrate how she traversed a racist and anti‐Black sporting workplace—where she was unfairly demonized
Aarti Ratna
wiley   +1 more source