Results 61 to 70 of about 502,227 (291)

Thermal Inactivation of Newcastle Disease Virus [PDF]

open access: yesApplied Microbiology, 1970
The rate of destruction of hemagglutinins and infectivity of Newcastle disease virus was determined over a temperature range of 37.8 to 60 C. From the calculated values of δH and δS, it was concluded that inactivation of the hemagglutinating activity and viral infectivity was due to protein denaturation.
J. T. R. Nickerson   +3 more
openaire   +3 more sources

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

open access: yesAdvanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng   +10 more
wiley   +1 more source

Noncytopathic mutants of Newcastle disease virus [PDF]

open access: yesJournal of Virology, 1978
We have isolated a novel class of mutants of Newcastle disease virus which are less cytopathic than their virulent parent but are still capable of infectious virus production. Unlike wild-type virus, the mutants did not form plaques after 2 days of incubation; they did, however, make hemadsorbing spots.
C H Madansky, M A Bratt
openaire   +3 more sources

Approaches to repurposing reverse transcriptase antivirals in cancer

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head   +2 more
wiley   +1 more source

Newcastle Disease Virus as a Vaccine Vector for Development of Human and Veterinary Vaccines

open access: yesViruses, 2016
Viral vaccine vectors have shown to be effective in inducing a robust immune response against the vaccine antigen. Newcastle disease virus (NDV), an avian paramyxovirus, is a promising vaccine vector against human and veterinary pathogens.
Shin-Hee Kim, S. Samal
semanticscholar   +1 more source

Harvesting AAV by tangential flow filtration using reverse asymmetric membranes

open access: yesBiotechnology Progress, EarlyView.
Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao   +5 more
wiley   +1 more source

Fifty Years of Clinical Application of Newcastle Disease Virus: Time to Celebrate!

open access: yesBiomedicines, 2016
This review provides an overview of 50 years of basic and clinical research on an oncolytic avian virus, Newcastle Disease Virus (NDV), which has particular anti-neoplastic and immune stimulatory properties.
V. Schirrmacher
semanticscholar   +1 more source

Phytochemistry, pharmacological insights, and food science applications of natural bioactive compounds from Ocimum species with a focus on essential oils

open access: yesFood Frontiers, EarlyView.
The article examines the phytochemistry, pharmacology, and food science applications of essential oils and extracts from Ocimum species (basil). It covers diverse extraction methods like hydrodistillation and microwave‐assisted extraction while discussing pharmacological benefits.
Oberdan Oliveira Ferreira   +13 more
wiley   +1 more source

GENETIC CHARACTERIZATION OF EGYPTIAN NEWCASTLE DISEASE VIRUS STRAINS ISOLATED FROM FLOCKS VACCINATED AGAINST NEWCASTLE DISEASE VIRUS, 2014-2015

open access: yesSlovenian Veterinary Research, 2018
In the present study, forty-five chicken flocks suspected to be infected with Newcastle disease virus (NDV) in Sharkia Governorate were submitted for clinical and postmortem examination as well as virus isolation and sero-molecular identification. Forty
Mohamed M. Megahed   +3 more
doaj   +1 more source

In Vitro Synergistic Enhancement of Newcastle Disease Virus to 5-Fluorouracil Cytotoxicity against Tumor Cells

open access: yesBiomedicines, 2016
Background: Chemotherapy is one of the antitumor therapies used worldwide in spite of its serious side effects and unsatisfactory results. Many attempts have been made to increase its activity and reduce its toxicity.
Ahmed Majeed Al-Shammari   +8 more
semanticscholar   +1 more source

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