Results 61 to 70 of about 6,518,230 (243)

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Histopathology of virulent Newcastle disease virus in immune broiler chickens treated with IMBO® [PDF]

Iraqi Journal of Veterinary Sciences, 2011
The effect of feed additive IMBO was investigated on histopathology of Newcastle disease virus in broiler chickens. Result osf this study showed no differences in histological changes of virulent Newcastle disease virus in vaccinated chickens treated ...
O. G. Mohammadamin, T. S. Qubih
doaj  

Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt, Richard Strasser, Christopher P. Garnham, Rima Menassa   +3 more
wiley   +1 more source

Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]

, 1975
The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
Kruse, F., U. Koszinowski, R. Thomssen, Koszinowski, Ulrich H., Thomssen, R., F. Kruse   +5 more
core   +1 more source

Newcastle disease vaccination program in broilers using a Apathogenic heat-resistant vaccine [PDF]

Archives of Razi Institute
The Newcastle disease (ND) is among the most common and deadly poultry diseases worldwide. Thermostable Newcastle disease virus (NDV) vaccines have been used widely to protect village chickens against Newcastle disease, due to their decreased dependence ...
Seyed Ali Ghafouri, Abolfazl Ghaniei, mozhgan moghani, Narges lotfalizadeh   +3 more
doaj   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

MULTIPLICITY REACTIVATION OF NEWCASTLE DISEASE VIRUS [PDF]

Journal of Bacteriology, 1962
Drake, John W. (University of Illinois, Urbana). Multiplicity reactivation of Newcastle disease virus. J. Bacteriol. 84: 352–356. 1962.—A very weak multiplicity reactivation occurs among Newcastle disease virus particles inactivated by ultraviolet irradiation.
openaire   +2 more sources

Isolation and Molecular Detection of Newcastle Disease Virus from Field Outbreaks in Chickens in Central Ethiopia

Veterinary Medicine: Research and Reports, 2022
Takele Worku,1 Morka Dandecha,2 Deraje Shegu,1 Abde Aliy,1 Demessa Negessu1 1Department of Virology and Molecular Biology, National Animal Health Diagnostic and Investigation Center, Sebeta, Oromia, Ethiopia; 2Department of Veterinary Laboratory ...
Worku T, Dandecha M, Shegu D, Aliy A, Negessu D   +4 more
doaj  

Food Safety Management and Mycotoxins Nexus: A Systematic Review of Mycotoxins Toxicity, Detoxification, Nutritional Impacts, and Economic Importance

Food Safety and Health, EarlyView.
The graphical abstract illustrates the interconnected relationship between food safety management, mycotoxin toxicity, and detoxification strategies, highlighting how preventive measures across the food chain can minimize mycotoxin contamination and reduce adverse health effects in humans/animals.
Chinaza Godswill Awuchi
wiley   +1 more source