Results 191 to 200 of about 4,421 (228)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Four clinical dilemmas in surgical decision making for low rectal cancer. [PDF]

Discov Oncol
Souadka A, Giger-Pabst U, Ouaissi M.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Comparative Evaluation of GPT-4 Turbo and Gemini-Pro in Medical Licensing Exams: Enhancing Artificial Intelligence's Role in Medical Education. [PDF]

Cureus
Sussan TT, Sussan RJ, Atkinson AG, Atkinson IH, Cunningham K, Eckroth J, Miller LB, Wei T.   +7 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Exploring Innovative Strategies to Enhance Electronic Health Record Interoperability in U.S. Healthcare Settings. [PDF]

Healthcare (Basel)
McPherson C, Davis R, Battu M, Lazar B.
europepmc   +1 more source

An online version and some updates of R package U.Taxonstand for standardizing scientific names in plant and animal species. [PDF]

Plant Divers
Zhang J, Qian H, Wang X.
europepmc   +1 more source

Peer-reviewed by human experts: AI failed in key steps to generate a scoping review on the neural mechanisms of cross-education. [PDF]

Eur J Appl Physiol
Morrone M, Hortobágyi T, Kidgell D, Farthing JP, Deriu F, Manca A.   +5 more
europepmc   +1 more source

HIV-1 Drug Resistance Trends in the Era of Modern Antiretrovirals: 2018-2024. [PDF]

Open Forum Infect Dis
Kagan RM, Baxter JD, Kim T, Marlowe EM.
europepmc   +1 more source

Stroke-related parameters affecting the deterioration of oral health-related quality of life as measured by OHIP-14 three months after ischemic stroke. [PDF]

BMC Oral Health
Slowik J, Wrona P, Homa T, Kolodziejczyk B, Dzierzak M, Dec-Cwiek M, Wnuk M.   +6 more
europepmc   +1 more source