Results 171 to 180 of about 95,713 (287)

A survey of newly recruited nurses’ perception and needs for scene simulation teaching of critical care hepatology

Chinese Journal of Integrative Nursing, 2022
Guihong NIAN, Lihua LU, Hengmei ZHU
openaire   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Development and efficacy evaluation of a competency-based training program for pediatric operating room nurses. [PDF]

Front Med (Lausanne)
Du Q, Wang Z, Xia M, Cao J, Liu Y, Jin Z, Yang X.   +6 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Patient Risk Identification Ability Among Newly Graduated Nurses: A Mixed-Methods Study. [PDF]

Risk Manag Healthc Policy
He L, Meng L, Tuo C, Tan R, Li M, Wei X.
europepmc   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

The Humanistic Care Behaviour of Head Nurses and the Influence on Stress and Transition Shock of New Nurses: A Cross-Sectional Study. [PDF]

Nurs Open
Luo Y, Yun B, Ling W, Fang W, Wang S, Zhen C, Li Y.   +6 more
europepmc   +1 more source

A longitudinal study on the prevention and intervention of burnout in newly recruited nurses: Part5

The Proceedings of the Annual Convention of the Japanese Psychological Association, 2011
Yoshifumi YAMAMOTO, Tokumi UENO, Shinya MASUDA   +2 more
openaire   +1 more source

Reducing overtreatment of older people near the end of life: the role of hospitals in a culture change [PDF]

, 2018
Alkhouri, Hatem, Cardona, Magnolia, Clark, Justin, Lewis, Ebony, Lovell, Nigel, Stehlik, Paulie   +5 more
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