Results 51 to 60 of about 154,220 (300)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Effectiveness of Structured Teaching Program on Nurses' Knowledge on Safe Handling of Psychotropic Drugs

open access: yesIndian Journal of Psychiatric Nursing, 2022
Background: Nurses play a major role in the management of psychiatric patients including the administration and handling of psychotropic drugs. They are in a pivotal position to educate the patient and family members about the medication and they should ...
S. V. Harsharaja   +4 more
doaj   +1 more source

Solving Colorado's Shortage of Health Professionals: Final Evaluation Findings and Recommendations [PDF]

open access: yes, 2009
This report shares evaluation findings from The Trust's Health Professions initiative, and recommends strategies to increase and sustain Colorado's health professions workforce.
Kaia Gallagher, Tanya Beer
core  

Health care professionals' perceptions towards lifelong learning in palliative care for general practitioners: a focus group study [PDF]

open access: yes, 2014
Background: There is a growing need for palliative care. The majority of palliative patients prefer their general practitioner (GP) to organize their palliative home care. General practitioners need a range of competences to perform this task.
Deveugele, Myriam   +5 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Psychological Feelings of Newly Recruited Nurses on the Implementation of One-to-One Specialized Tutorial System Training: A Qualitative Research

open access: yes, 2020
Background: Clinical tutors play an important role and responsibility in the clinical training of nurses,They are indispensable members of clinical education training and the soul of continuing education training.
Yanfei Li   +3 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Migrant Workers in the North East of England [PDF]

open access: yes, 2005
This report is the supplementary report of the 'Organising Migrant Workers in Construction' project. It is a descriptive account of the nationality, location, sector of work and companies of migrant workers living in the North East of England.
Fitzgerald, Ian
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

International and industry partnerships: Building nursing capacity in Thailand [PDF]

open access: yes, 2006
A newly formed partnership between Edith Cowan University, the Ministry of Public Health in Thailand, a College of Nursing and two major hospitals in Bangkok is building capacity within Thai Nurses to manage mental health problems and HIV/AIDS.
Churchouse, Christopher Lee   +2 more
core   +1 more source

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