Results 211 to 220 of about 6,586,077 (324)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
A linguistic comparison between human- and AI-generated content. [PDF]
iScienceRodrigues FA, Sturm NF, Pinheiro FL.
europepmc +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Advertising Payments to News Websites That Publish Health Misinformation.
JAMA Netw OpenPatel NG, Ramachandran R, Ross JS.
europepmc +1 more source
Comparative prognostic performance of identification of seniors at risk tool and national early warning score for 30-day adverse outcomes in older emergency department patients. [PDF]
BMC Emerg MedAksu ŞH +5 more
europepmc +1 more source