Results 81 to 90 of about 2,345,138 (294)
In-Person and Online Studies Examining the Influence of Problem Solving on the Fading Affect Bias
Behavioral SciencesThe fading affect bias (FAB) occurs in autobiographical memory when unpleasant emotions fade faster than pleasant emotions and the phenomenon appears to be a form of emotion regulation.
Jeffrey Alan Gibbons +4 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
EnergiesThe growing population and increasingly competitive economic climate have increased the demand for alternative fuel sources, with hydrogen being one of the more viable options.
Erik Biehler +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Instanton effects in twist-3 generalized parton distributions
Physics Letters BThe instanton vacuum picture is used to study hadronic matrix elements of the twist-3 (dimension-4, spin-1) QCD operators measuring the quark spin density and spin-orbit correlations.
June-Young Kim, Christian Weiss
doaj +1 more source
Revista Espaço Acadêmico, 2021 Os finais felizes não são sempre iguais. Pra falar a verdade, eles nem sempre são felizes. As pessoas em geral têm muitas ideias estranhas sobre os filmes de Hollywood, e nem sempre fica muito claro o que as pessoas querem fizer com o termo. “Hollywood”
Michael Barret
doaj
, 1900 Image of the Dallas Morning News building with a group of men standing in the street in front of it.Title from finding aid. Recto: [typewritten on label affixed to original photograph] No. 1267. The Dallas News about 1900.
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FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source