Results 51 to 60 of about 2,942,401 (279)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
UAV collision avoidance: a specific acceleration matching approach [PDF]
, 2011 Includes abstract.Includes bibliographical references.An increased level of autonomy is required for future Unmanned Aerial Vehicle (UAV) missions. One of the technologies required for this to occur is an adequate sense and avoid system to enable the UAV
Patel, Amir
core +1 more source
Scrolling away from the news: how news overload drives avoidance and curation in the UAE
Cogent Arts & HumanitiesThe huge increase in news content in the fast-changing world of social media has resulted in the phenomenon of news overload. This is reflected in individual behaviours such as news curation or avoidance, which have become a significant issue in both ...
Amr Mohamed Mahmoud Abdelhamid +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
May Understand, but Cannot Relate: How Do News Avoiders and Doomscrollers Perceive Each Other?
Социология властиThis article examines two opposing media consumption trends—news avoidance and doomscrolling—through the lens of media environment and societal fragmentation.
A. D. Kazun, D. V. Petrova
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Automatic collision avoidance: towards the 21st century
, 1995 The importance of collision avoidance at sea is emphasised to cover four main aspects. A brief review of the research that has been carried out on automatic collision avoidance systems follows.
Wilson, P.A., Zhao, J., Price, W.G.
core +1 more source
Will News Find Them With Generative AI?
Weizenbaum Journal of the Digital SocietyThree key affordances of generative AI (GenAI), namely, hyper-personalization, intuitive interaction, and universality, provide the technology with the potential to disrupt current news consumption practices.
Michael V. Reiss +3 more
doaj +1 more source
CommunicationsAbstract In this paper, we explore the complex relationship between news use and intentional news avoidance. Based on a survey conducted ( N = 2,798) in the Netherlands and a latent profile analysis, we first identified nine different types of news users.
Rens Vliegenthart +3 more
openaire +2 more sources