Results 71 to 80 of about 2,942,401 (279)

INFORMATION AVOIDANCE BEHAVIOR REGARDING HOAXES INDICATORS

open access: yesJurnal Psikologi Undip, 2020
Hoaxes have become a common phenomenon in Indonesia. The Indonesian Telematics Society Survey shows that even though Indonesian people understand the way in recognizing hoaxes, they Indonesia are not sure of being able to immediately recognize hoaxes ...
Raymond Godwin   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Constitution and Bylaws of The Pioneers of Newport News

open access: yes, 1914
This is the image of a small booklet containing the constitution and bylaws of the Pioneers Club of Newport News, Virginia. The Pioneers Club was an association of men who had lived a long period of time in Newport News, Virginia and had made ...
The Pioneers of Newport News
core   +1 more source

Source Credibility Matters: Does Automated Journalism Inspire Selective Exposure?

open access: yesInternational Journal of Communication, 2021
To examine whether selective exposure occurs when people read news attributed to an algorithm author, this study conducted a 2 (author attribution: human or algorithm) × 3 (article attitude: attitude-consistent news, attitude-challenging news, or neutral
Chenyan Jia, Thomas J. Johnson
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

What Does it Take to Sustain a News Habit? The Role of Civic Duty Norms and a Connection to a "News Community" Among News Avoiders in the UK and Spain

open access: yesInternational Journal of Communication, 2020
Why do some people maintain a news habit while others avoid news altogether? To explore that question, we put findings from an interview-based study of news avoiders in the UK and Spain into dialogue with past research on factors found to shape news ...
Ruth Palmer, Benjamin Toff
doaj  

Feel, think, avoid: Testing a new model of advertising avoidance

open access: yesJournal of Marketing Communications, 2019
Advertising avoidance is perhaps one of the greatest challenges facing marketers today. This study investigates the impact of emotions on advertising avoidance in social media. It tests five antecedents and two types of advertising avoidance, developing a new model of advertising avoidance. Data were collected via an online survey of 849 Facebook users
Louise Kelly   +3 more
openaire   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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