Results 31 to 40 of about 4,534,038 (300)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Both Facts and Feelings: Emotion and News Literacy

Journal of Media Literacy Education, 2018
News literacy education has long focused on the significance of facts, sourcing, and verifiability. While these are critical aspects of news, rapidly developing emotion analytics technologies intended to respond to and even alter digital news audiences ...
Susan Currie Sivek
doaj   +1 more source

Political Polarization in Online News Consumption

Proceedings of the International AAAI Conference on Web and Social Media, 2021
Political polarization appears to be on the rise, as measured by voting behavior, general affect towards opposing partisans and their parties, and contents posted and consumed online. Research over the years has focused on the role of the Web as a driver of polarization.
Kiran Garimella 0001, Tim Smith, Rebecca Weiss, Robert West 0001   +3 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Volunteering for the greater good reduces individuals' dependency on news consumption during crises, improves quality of life and resilience

Computers in Human Behavior Reports
Social media is a major source of news consumption. During periods of crises, its use may lead to information overload which may result in higher levels of stress. In this study we explore the effect of various forms of news consumption during war.
Hila Chalutz-BenGal, Oriel Singer, Alon Sela   +2 more
doaj   +1 more source

The Consumption of New Psychoactive Substances and Methamphetamine [PDF]

Deutsches Ärzteblatt international, 2018
The abuse of new psychoactive substances (NPS) and methamphetamine has severe adverse effects. Here we provide the first report of regional patterns in NPS and methamphetamine consumption in Germany, on the basis of epidemiologic data from six federal states (Bavaria, Hamburg, Hesse, North Rhine-Westphalia, Saxony, and Thuringia).Data were derived from
Elena Gomes, de Matos, Tessa-Virginia, Hannemann, Josefine, Atzendorf, Ludwig, Kraus, Daniela, Piontek   +4 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Exploring the antecedents of news avoidance behavior among university students in Pakistan [PDF]

World of Media
News avoidance has emerged as a growing concern, influencing how information is received, shaping civic engagement, and forming individual perspectives.
Filza Imran, Farahat Ali
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Will News Find Them With Generative AI?

Weizenbaum Journal of the Digital Society
Three key affordances of generative AI (GenAI), namely, hyper-personalization, intuitive interaction, and universality, provide the technology with the potential to disrupt current news consumption practices.
Michael V. Reiss, Eva Luise Knor, Lisa Merten, Judith Möller   +3 more
doaj   +1 more source