Results 141 to 150 of about 5,240,308 (402)

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Deep Cross-media Knowledge Transfer [PDF]

open access: yesarXiv, 2018
Cross-media retrieval is a research hotspot in multimedia area, which aims to perform retrieval across different media types such as image and text. The performance of existing methods usually relies on labeled data for model training. However, cross-media data is very labor consuming to collect and label, so how to transfer valuable knowledge in ...
arxiv  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Critical discourse analysis of presidential candidates TV debates between Ebrahim Raisi and Abdolnaser Hemmati in Iran’s 2021 presidential election

open access: yesSocial Sciences and Humanities Open
This study conducts a Critical Discourse Analysis of the televised presidential debates between Iranian candidates Ebrahim Raisi and Abdolnaser Hemmati. Utilizing linguistic devices from Teun A.
Hamid Reza Rahro   +2 more
doaj  

CIMTDetect: A Community Infused Matrix-Tensor Coupled Factorization Based Method for Fake News Detection

open access: yes, 2018
Detecting whether a news article is fake or genuine is a crucial task in today's digital world where it's easy to create and spread a misleading news article.
Gupta, Shashank   +3 more
core   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

From everyday communicative figurations to rigorous audience news repertoires: A mixed method approach to cross-media news consumption

open access: yesMedieKultur: Journal of Media and Communication Research, 2016
In the last couple of decades there has been an unprecedented explosion of news media platforms and formats, as a succession of digital and social media have joined the ranks of legacy media.
Christian Kobbernagel   +1 more
doaj   +1 more source

Understanding the Participatory News Consumer [PDF]

open access: yes, 2010
Analyzes survey findings on the impact of social media and mobile connectivity on news consumption behavior by demographics and political affiliation.
Amy Mitchell   +4 more
core  

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

Longitudinal predictors of weapon involvement in middle adolescence: Evidence from the UK Millennium Cohort Study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 5-14, January 2023., 2023
Abstract This study uses longitudinal data from the UK Millennium Cohort Study (N = 13,277) to examine the childhood and early adolescence factors that predict weapon involvement in middle adolescence, which in this study is exemplified by having carried or used a weapon.
Aase Villadsen, Emla Fitzsimons
wiley   +1 more source

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