Results 231 to 240 of about 120,572 (300)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Media Effects, Interpersonal Communication and Beyond: An Experimental Approach to Study Conversations About the Media and Their Role in News Reception

, 2013
Denise Sommer
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

News Media Framing of Suicide Circumstances and Gender: Mixed Methods Analysis.

JMIR Ment Health
Foriest JC, Mittal S, Kim E, Carmichael A, Lennon N, Sumner SA, De Choudhury M.   +6 more
europepmc   +1 more source

A decade of PrEP: the evolution of HIV pre-exposure prophylaxis content and sentiments in South African print news media, 2012-2021. [PDF]

Cult Health Sex
Coelho SM, Rosen JG, Schulz G, Meek K, Shipp L, Singh C, Willis K, Best A, Mcingana M, Mcloughlin J, Hausler H, Beyrer C, Baral SD, Schwartz SR.   +13 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Real-Time Exposure to Negative News Media and Suicidal Ideation Intensity Among LGBTQ+ Young Adults.

JAMA Pediatr
Clark KA, Kellerman JK, Argiros AP, Phillips KL, Park EC, Cyperski M, Pachankis JE, Kleiman E.   +7 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Drivers of vulnerability to medicine smuggling and combat strategies: a qualitative study based on online news media analysis in Iran. [PDF]

BMC Health Serv Res
Fakhrzad N, Yazdi-Feyzabadi V, Fakhrzad M.   +2 more
europepmc   +1 more source

“VILLAIN” VS. “VICTIM”: A NEWS HEADLINE ANALYSIS AND LITERATURE REVIEW OF CANADIAN NEWS PRINT MEDIA IN REPRESENTING REFUGEES AND FRAMING CANADIAN PERCEPTIONS OF REFUGEES

, 2017
Tsering Kalden Lama
openalex   +1 more source