Results 41 to 50 of about 105,633 (267)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Design of news sentiment classification and recommendation system based on multi-model fusion and text similarity

open access: yesInternational Journal of Cognitive Computing in Engineering
To improve the performance of the news recommendation system, the study employs a multi-model fusion strategy in conjunction with three classification methods to improve the accuracy of sentiment classification.
Qinchen Xi, Peiyun Jiang
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cross-Platform News Media Repertoires and Their Political Implications

open access: yesInternational Journal of Communication, 2021
With the expansion of news media platforms, news media usage patterns and their implications on civic and political engagement have become complex. To better understand these complexities, this study examines cross-platform news media repertoires and ...
Su Jung Kim, Lena-Maria Schwarze
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Hashtag activism and feminisms: a study on the Sabarimala temple entry in India

open access: yesCogent Arts & Humanities
Feminism in India has been evolving in recent decades, with acknowledgment of intersectionality, the dynamic interrelationship between caste, class, religious and regional identities in media representations of women.
Swapna Gopinath, Neha Jindal
doaj   +1 more source

RESEARCH AND PRACTICE OF THE NEWS MAP COMPILATION SERVICE [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2018
Based on the needs of the news media on the map, this paper researches on the news map compilation service, conducts demand research on the service of compiling news maps, designs and compiles the public authority base map suitable for media publication,
T. Zhao, W. Liu, W. Ma
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Dehazing algorithm for complex environment video images considering visual communication effects

open access: yesJournal of Radiation Research and Applied Sciences
The communication effect of outdoor computer vision systems is closely related to the dehazing performance of video images. Currently, video image restoration methods in complex environments are still in an urgent development stage.
Yisa Yu, Jianwen Li
doaj   +1 more source

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