Results 51 to 60 of about 39,334 (261)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

It’s Not Just “8 Dead”: Examining News and Twitter’s Social Construction of the Atlanta Spa Shootings Through the Lens of Networked Gatekeeping and Affective Publics

Social Media + Society
Drawing from the theories of networked gatekeeping and affective publics, this study compares how news media and social media users shaped the discourse surrounding the 2021 Atlanta spa shootings.
Gyo Hyun Koo, Bin Chen
doaj   +1 more source

Breaking the news or fueling the epidemic? Temporal association between news media report volume and opioid-related mortality. [PDF]

PLoS ONE, 2009
BACKGROUND:Historical studies of news media have suggested an association between reporting and increased drug abuse. Period effects for substance use have been documented for different classes of legal and illicit substances, with the suspicion that ...
Nabarun Dasgupta, Kenneth D Mandl, John S Brownstein   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Social media filtering of sensationalistic news on spiders—A global overview

People and Nature
The interplay between traditional and social media is a critical aspect of information dissemination. Acting as news filters, social media platforms can amplify the visibility of specific content and shape emotions towards wildlife. Widely feared animals
Veronica Nanni, Irene Moioli, Catherine Scott, Stefano Mammola   +3 more
doaj   +1 more source

Assessing the Dissemination of Federal Risk Communication by News Media Outlets During Enteric Illness Outbreaks: Canadian Content Analysis

JMIR Public Health and Surveillance
BackgroundEffective dissemination of federal risk communication by news media during multijurisdictional enteric illness outbreaks can increase message reach to rapidly contain outbreaks, limit adverse outcomes, and promote informed decision-making by ...
Hisba Shereefdeen, Lauren Elizabeth Grant, Vayshali Patel, Melissa MacKay, Andrew Papadopoulos, Leslie Cheng, Melissa Phypers, Jennifer Elizabeth McWhirter   +7 more
doaj   +1 more source

News media coverage of extreme risk protection order policies surrounding the Parkland shooting: a mixed-methods analysis

BMC Public Health, 2021
Background Following the 2018 mass shooting at Marjory Stoneman Douglas High School in Parkland, Florida, there was a dramatic increase in media coverage of extreme risk protection orders (ERPOs) and in state policy proposals for ERPO laws.
Rocco Pallin, Amanda J. Aubel, Christopher E. Knoepke, Veronica A. Pear, Garen J. Wintemute, Nicole Kravitz-Wirtz   +5 more
doaj   +1 more source

Social Media Sharing of Articles About Measles in a European Context: Text Analysis Study

Journal of Medical Internet Research, 2021
BackgroundDespite the existence of an effective vaccine, measles still threatens the health and lives of many Europeans. Notably, during the COVID-19 pandemic, measles vaccine uptake declined; as a result, after the pandemic ...
Dominik Wawrzuta, Mariusz Jaworski, Joanna Gotlib, Mariusz Panczyk   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source