Results 81 to 90 of about 858,737 (291)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

How does the media contribute to the rise of hate crimes against foreign domestic helpers in Hong Kong? An unfair problem frame and agenda setting

open access: yesFrontiers in Sociology
Hate crimes are widespread in Hong Kong society. Foreign domestic helpers working in Hong Kong also experience unfair agenda-setting by the media due to their dual economic and social disadvantages, and the media tries to portray them in a hostile social
Zhuoli Chen
doaj   +1 more source

Global connectivity through news: aspiration or fantasy? [PDF]

open access: yes, 2010
Here are some draft notes for a paper I am writing on how people in the UK use the news media in an age of globalised communication. It’s taken out of context from the rest of the paper, but if it sparks any thoughts, or if you have any comments or ideas
Beckett, Charlie
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

PENINGKATAN KETERAMPILAN MENULIS TEKS BERITA MENGGUNAKAN METODE OBSERVASI LAPANGAN DAN MEDIA BERBASIS TEKNOLOGI

open access: yesJurnal Edukasi Khatulistiwa: Pembelajaran Bahasa dan Sastra Indonesia, 2018
The aim of this research is to describe the improvement of the students' ability of writing text news with the field observation method and technology media for students in grade 8 smp n 1 ella hilir melawi recency.
Kaini Kaini
doaj   +1 more source

In the blood [PDF]

open access: yes, 2017
Access to thesis permanently restricted to Ball State community only.This creative project is a short story about a small town in Wisconsin that is suffering from a modern-day diphtheria outbreak.
McAlister, Meagan L.
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Kony2012 and the digital challenge to the public sphere (new research paper) [PDF]

open access: yes, 2012
This is a short early draft extract from a much longer paper I am writing for the International Broadcasting Trust on the future of the ‘public sphere’ in the digital age.
Beckett, Charlie
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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