Results 101 to 110 of about 73,385 (311)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The Northern Territory news Fri 18 Dec 2015
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Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Deu no Blog Jornalístico: é notícia?
In the web, many are the news sites whose staff journalists keep blogs. The goal of this article is trying to answer the following questions: what is "news" for these blogs? Why are they called blogs?
Claudia Irene de Quadros +1 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Women Representation in Iranian News Sites: A Case Study of Four News Sites
This paper aims to provide an analysis of the content and topic of four Iranian news sites. The framework of this research is based on agenda setting theory and it is used to analyse the effect of this theory on defining and choosing news that are ...
Dr Hadi Khaniki +2 more
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Politics and Incivility in the Online Comments: What is Beyond the Norm-Violation Approach?
The article offers an empirical analysis of the disrespectful online comments—in total, 17,581,659—in Hungary between 2017 and 2019. Considering the name-calling and obscene and abusive phrases as communication practice, we rely on computational ...
Gabriella Szabó +2 more
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In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Four Irish sites participate in Hep C trial.
Four of Ireland’s major academic teaching hospitals have participated in a trial on a new hepatitis C drug regime that promises to revolutionise the future treatment of the disease.
Gantly, Dara
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