Results 121 to 130 of about 73,385 (311)

An analysis of community news web sites : a comparison of local news web sites to indicate industry trends

open access: yes, 2011
The purpose of this creative project is to explore the habits of online community news Web sites. Specifically, this study looked at two community news Web sites to examine the aesthetics and content of community news online.
Kerman, Jessica F.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Geomorphic Settings of Known Archaeological Sites in the Lower Grand River Valley, Ottawa County, Michigan

open access: yes, 2010
To predict undiscovered archaeological sites in the Lower Grand River, we mapped known archaeological sites using color and infrared aerial photos, digital raster graphics, and digital elevation models.
Hansen, Nathaniel J.
core  

A dinâmica da notícia nas redes sociais na internet [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Jornalismo, Florianópolis, 2013.Esta pesquisa tem como objeto de estudo a dinâmica da notícia nas redes sociais na internet ...
Sousa, Maíra de Cássia Evangelista de
core  

An evaluation of online information acquisition in US news deserts

open access: yesScientific Reports
A growing concern is that as local newspapers disappear, communities lose trusted gatekeepers and develop information voids, creating openings for misinformation to thrive.
Kevin T. Greene   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A digital news snapshot: an analysis of 25 of the top sites across platforms [PDF]

open access: yes, 2016
An increasing amount of news traffic is coming from smartphones and tablets, as opposed to laptop and desktop computers. As news habits change, it is important to understand what is available for news audiences across various platforms.
Natalie Jomini Stroud   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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