Results 61 to 70 of about 73,385 (311)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
News consumption patterns in Iceland
News consumption has changed dramatically in the digital age, becoming increasingly complicated and fragmented. In this study, I analyse news consumption patterns in Iceland, drawing on data from a survey conducted in 2017, and compare it with news ...
Jóhannsdóttir Valgerður
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Automatic web content extraction for generating tag clouds from Thai web sites
This paper proposes a novel Web content extraction approach based on heuristic rules and the XPath utility in XML. The main objective is to address the problem of Web visualization by generating tag clouds from Thai Web sites in order to provide an ...
Wigrai Thanadechteemapat +3 more
core +1 more source
Picturing the World's news: news photography, culturalproduction, Thomson Reuters and the international processof news making [PDF]
In this research the production process of news pictures at Thomson Reuters international multimedia news agency is examined along its ‘local’ and ‘international’ key moments and sites, and the career of Reuters photographs- from the moment they are ...
Ilan, J.
core +1 more source
Citation.js: New site I recently updated the website of Citation.js. This involved getting rid of the Material Design Lite framework, simplifying and refreshing the site design and modernisering some of the code behind it. Additionally, I updated the content of the homepage, and added some functionality to the interface of the blog page and the demo.
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
textThis study builds the constructs of three kinds (four types) of gated news to explore how online users pay attention to three online mainstream news sites by defining online users from marketing, democratic, and technological perspectives.
Chen, Ying-Ying, 1966-
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

