Results 71 to 80 of about 73,385 (311)
World Heritage: Challenges for the Millennium [PDF]
, 2007 This 200-page publication provides a comprehensive overview and analysis of more than three decades of the implementation of the World Heritage Convention and highlights a number of its successes and challenges.
Labadi, Sophia
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Social media sites 'make addictive medication easier to buy'.
, 2018 Addiction psychiatrist Dr Colin O'Gara believes social media sites have "opened the door" for prescription drug dealers to thrive.
Begley, Ian
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
, 2009 The central contention of this thesis is that an increase in image-focused or pseudo-event-focused hyperlinked-headlines is occurring on online news sites. This central contention contains at least three implications. First, holding that the newspaper is
Studinski, David P.
core
Negative online news articles are shared more to social media
Scientific ReportsPrior research demonstrates that news-related social media posts using negative language are re-posted more, rewarding users who produce negative content.
Joe Watson +3 more
doaj +1 more source
Social Media + Society, 2017 In this article, we present a cross-national comparative analysis of which online news users in practice engage with the participatory potential for sharing and commenting on news afforded by interactive features in news websites and social media ...
Antonis Kalogeropoulos +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source