Results 121 to 130 of about 1,436,799 (320)

Recruitment and eligibility in a Phase 1 early Alzheimer's disease trial of Sabirnetug

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION Historically underrepresented racial and ethnic groups may face a higher risk and burden of dementia but continue to be underrepresented in Alzheimer's disease (AD) clinical research.
Robyn Moxon, Todd Feaster, Gopalan Sethuraman, Alyssa Carroll, Siew Tin Gan, Vladimir Skljarevski, Karen Sundell, Janice Hitchcock, Eric Siemers   +8 more
doaj   +1 more source

Uso de diferentes tipos de calçados não interfere na postura ortostática de mulheres hígidas

Fisioterapia em Movimento
INTRODUÇÃO: Nos últimos anos, as mulheres passaram a usar sapatos de salto para ficarem mais bonitas. Entretanto, tal hábito desencadeou vários efeitos negativos para o sistema musculoesquelético.
Geraldo Fabiano de Souza Moraes, Adriana Papini Antunes, Elaine Souza Rezende, Poliana Cardoso Ribeiro de Oliveira   +3 more
doaj   +1 more source

Rib‐Reinforced Ultralight and Ultra‐Strong Shell Lattices

Advanced Science, EarlyView.
This study thoroughly reveals the relation between the curvature and stress direction of triply periodic minimal surface (TPMS) thin shell lattices and proposes a novel rib reinforcement design strategy to incorporate ribs along the line of asymptotes (LOA) and the line of principal curvatures (LOC) to enhance the strength of ultralight TPMS shell ...
Winston Wai Shing Ma, Lei Zhang, Junhao Ding, Shuo Qu, Michael Yu Wang, Xu Song, Ming Wang Fu   +6 more
wiley   +1 more source

Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries

Advanced Science, EarlyView.
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang, Wenkai Wang, Zhenling Peng, Jianyi Yang   +3 more
wiley   +1 more source

Programmable Multifunctional Bistable Structures for Energy Transfer and Dissipation

Advanced Science, EarlyView.
Utilizing the energy conversion characteristics of asymmetric bistable beams, this study develops a programmable multifunctional system composed of multiple bistable beams for energy transfer and dissipation. The high energy density enables the system to demonstrate potential in transient scenarios such as target delivery and shock absorption ...
Xin Na, Jincong Zhang, Zhicheng Chen, Venkatarao Selamneni, Haotian Chen, Hadi Heidari, Morteza Amjadi   +6 more
wiley   +1 more source

A Microfiber‐Reinforced Janus Hydrogel E‐Skin With Recyclable Feature for Multimodal Sensing and Gender‐Specific Physiological Monitoring

Advanced Science, EarlyView.
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding, Yufeng Li, Shaozhe Tan, Jiachun Sun, Xu Yang, Xuesi Zhang, Zhenhua Lin, Zhenyu Li, Yue Hao, Yannan Liu, Yingchun Li, Jingjing Chang   +11 more
wiley   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Salt Water Drops Slide Faster: Ionic Modulation of Drop Friction

Advanced Science, EarlyView.
Salt ions markedly accelerate water drops on conductive substrates coated with nanometer‐thin hydrophobic layers. Across diverse electrolytes and surfaces, higher ion concentration consistently lowers kinetic friction by reducing contact angle hysteresis.
Dongho Shin, Rutvik Lathia, Chirag Hinduja, Hyunbae Cheon, Seongmin Park, Hans‐Jürgen Butt, Junwoo Park   +6 more
wiley   +1 more source

The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models

Frontiers in Behavioral Neuroscience
We employed a structural bioinformatics approach to develop novel peptides with predicted affinity to the binding site for negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGluR5).
Anton V. Malyshev, Vsevolod V. Pavshintcev, Nikita A. Mitkin, Iuliia A. Sukhanova, Vasilina R. Gedzun, Alexander S. Zlobin, Igor I. Doronin, Gennady A. Babkin, Tomi K. Sawyer   +8 more
doaj   +1 more source

Enhanced Energy Harvesting Performance of Biodegradable Polylactic Acid/3D Anodic Aluminum Oxide Composite Triboelectric Nanogenerators

Advanced Electronic Materials, EarlyView.
Polylactic acid (PLA) embedded in 3D anodic aluminum oxide (3D‐AAO) yields triboelectric nanogenerators (TENGs) with ɛeff = 5.1, delivering 20V and 108µW both per cm2. These agglomeration‐resistant, compostable/biocompatible devices retain 95% output after 104 cycles, enabling robust self‐powered Internet of Things (IoT) sensing.
Carlos G. Cobos, Catia Rodrigues, Mariana M. Ramos, João Ventura, André M. Pereira, Marisol Martín‐González   +5 more
wiley   +1 more source