Results 71 to 80 of about 980 (183)

Standing on a common ground: a comparison of static stability approaches for pallet loading

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract At the practical level, the static stability constraint is one of the most important constraints in practical pallet loading problems, such as air cargo palletizing. Approaches to modeling static stability, which range from base support and mechanical equilibrium calculations to physical simulation, differ in workflow, focus, and assumptions ...
Philipp G. Mazur   +3 more
wiley   +1 more source

Scratching beneath the surface: Quantification of muscle architecture and myosin heavy chain content in the forelimbs of black‐tailed prairie dogs (Cynomys, Rodentia)

open access: yesJournal of Anatomy, EarlyView.
Black‐tailed prairie dogs are highly social ground squirrels that excavate communal burrow systems, most often in medium‐textured soils. Their forelimbs demonstrate morphofunctional trade‐offs for scratch‐digging and terrestrial ecology, including well‐developed and fast‐contracting proximal musculature with large mechanical advantage paired with ...
Luke A. Scheetz   +4 more
wiley   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger   +4 more
wiley   +1 more source

A Fully Automated Pipeline for Vertebral Structural Assessment From Medical Images. Application Under Metastatic Conditions

open access: yesInternational Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 7, July 2026.
We present an automated CT‐to‐simulation workflow to estimate structural response and fracture risk in metastasis‐affected vertebrae. Deep learning performs vertebral identification and segmentation, while CPD assigns geometry‐aware boundary conditions.
B. Gandia‐Vañó   +4 more
wiley   +1 more source

General Framework for Multi‐Degree‐of‐Freedom Stiffness Matrix Updating for Iterative Solution Algorithms in Hybrid Simulation

open access: yesEarthquake Engineering &Structural Dynamics, Volume 55, Issue 9, Page 1947-1967, 25 July 2026.
ABSTRACT Iterative solvers are advantageous for handling nonlinear structural analysis problems. The iterative solvers often require updating the stiffness matrix, which limits their application in static and pseudo‐dynamic hybrid simulations because: (1) updating the stiffness matrix of a system involving a physical specimen is challenging; (2 ...
Junyan Xiao, Oh‐Sung Kwon, Evan Bentz
wiley   +1 more source

Local Polynomial Regression and Filtering for a Versatile Mesh‐Free PDE Solver

open access: yesInternational Journal for Numerical Methods in Fluids, Volume 98, Issue 7, Page 804-839, July 2026.
A high‐order, mesh‐free finite difference method for solving differential equations is presented. Both derivative approximation and scheme stabilisation is carried out by parametric or non‐parametric local polynomial regression, making the resulting numerical method accurate, simple and versatile. Numerous numerical benchmark tests are investigated for
Alberto M. Gambaruto
wiley   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 921-944, July 2026.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano   +4 more
wiley   +1 more source

Phase‐Pole‐Free Images and Smooth Coil Sensitivity Maps by Regularized Nonlinear Inversion

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 1, Page 134-145, July 2026.
ABSTRACT Purpose Phase singularities are a common problem in image reconstruction with auto‐calibrated sensitivities due to an inherent ambiguity of the estimation problem. The purpose of this work is to develop a method for detecting and correcting phase poles in non‐linear inverse (NLINV) reconstruction of MR images and coil sensitivity maps ...
Moritz Blumenthal, Martin Uecker
wiley   +1 more source

Introduction to TREx‐ATM V2.0: A Versatile Model of Auroral Transport and Its Effects in the Ionosphere

open access: yesEarth and Space Science, Volume 13, Issue 7, July 2026.
Abstract Auroral transport models (ATMs) play an important role in quantitative studies of optical auroras, their driving mechanisms, and their effects on the ionosphere and thermosphere. TREx‐ATM was initially developed as the support model for the Transition Region Explorer (TREx) mission, and has gained increasing applications in the community in ...
Jun Liang   +5 more
wiley   +1 more source

A Data‐Driven Multiscale Scheme for Anisotropic Finite Strain Magneto‐Elasticity

open access: yesInternational Journal for Numerical Methods in Engineering, Volume 127, Issue 12, 30 June 2026.
ABSTRACT In this work, we develop a neural network‐based, data‐driven, decoupled multiscale scheme for the modeling of structured magnetically soft magnetorheological elastomers (MREs). On the microscale, sampled magneto‐mechanical loading paths are imposed on a representative volume element containing spherical particles and an elastomer matrix, and ...
Heinrich T. Roth   +4 more
wiley   +1 more source

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