Results 41 to 50 of about 11,303,291 (302)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Combined Conjugate Gradient Quasi-Newton Method with Modification BFGS Formula

open access: yesInternational Journal of Analysis and Applications, 2023
The conjugate gradient and Quasi-Newton methods have advantages and drawbacks, as although quasi-Newton algorithm has more rapid convergence than conjugate gradient, they require more storage compared to conjugate gradient algorithms.
Mardeen Sh. Taher, Salah G. Shareef
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

A Newton Method for Linear Programming [PDF]

open access: yes, 2002
A fast Newton method is proposed for solving linear programs with a very large ( 106) number of constraints and a moderate ( 102) number of variables. Such linear programs occur in data mining and machine learning.
O. L. Mangasarian, Mangasarian, Olvi
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Local convergence for composite Chebyshev-type methods

open access: yesCommunications in Advanced Mathematical Sciences, 2018
We replace Chebyshev's method for solving equations requiring the second derivative by a Chebyshev-type second derivative free method. The local convergence analysis of the new method is provided using hypotheses only on the first derivative in contrast ...
Santhosh George, İoannis K Argyros
doaj   +1 more source

A new approach for the bigeometric newton method

open access: yesMANAS: Journal of Engineering, 2023
In this study, quadratic convergent new bigeometric Newton's method (nBGNM) was developed. For this, the basic definitions and theorems of bigeometric analysis, which is one of the non-Newtonian analysis, were used. Using the bigeometric Taylor expansion,
Numan Yalçın, Ercan Celık
doaj   +1 more source

The Shadow of the Soul Breaker: Solitary Confinement, Cocaine, and the Disintegration of Huey P. Newton [PDF]

open access: yes, 2015
The article probes the impact of prison on Huey P. Newton, founder of the Black Panther Party. Incarcerated for three years in various locations in California, Newton descended into cocaine addiction and criminality soon after his 1970 release.
Street, Joe
core   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

open access: yesArthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk   +7 more
wiley   +1 more source

Filtered-Stochastic-Newton

open access: yes, 2022
We apply sequential Bayesian inference with a discriminatively specified observation model to the subsampled gradients and Hessians used by the stochastic Newton method for online ...
Michael C. Burkhart (6643982)
core   +1 more source

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