Results 241 to 250 of about 1,460,723 (393)

Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids

open access: yesNature Network Boston, 2020
W. Gu   +21 more
semanticscholar   +1 more source

Benchmarking accelerated next-generation sequencing analysis pipelines. [PDF]

open access: yesBioinform Adv
Samarakoon PS   +11 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer [PDF]

open access: gold, 2010
Juliann Chmielecki   +8 more
openalex   +1 more source

Role of Next-Generation Sequencing in Diagnosis of Familial Hypercholesterolemia in Serbia. [PDF]

open access: yesDiagnostics (Basel)
Lukac SS   +7 more
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study

open access: yesNature Biotechnology, 2021
J. Foox   +26 more
semanticscholar   +1 more source

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